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Immunotoxicology And Immunopharmacology
The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
T Lymphocytes Subpopulations in Immunotoxicology
Den T-Lymphocyten kommt eine Schlüsselrolle im Immunsystem zu: Sie sind unter anderem für Resistenzen gegenüber Infektionen und Tumoren und für die Entwicklung von Allergien und Autoimmunität verantwortlich. Bisher gab es kein vergleichbares Buch, das Funktionen und Subpopulationen der T-Zellen wie das vorliegende Werk von immunbiologischen Grundlagen ausgehend zusammenfassend darstellt.(05/98)
Toxicology of Chemical Respiratory Hypersensitivity
An overview of respiratory asthma is included in this text, which examines aspects of chemical respiratory allergy and occupational asthma caused by exposure to chemicals. It covers occupational safety measures, and methods for identifying and characterizing chemical allergens.
Immunotoxicology and Immunopharmacology
Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history,
Immunotoxicology and Immunopharmacology, Third Edition
Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history, an entire section covers the phylogeny and ontogeny of the immune system, spanning levels of biological complexity from earthworms to marine mammals.
Dermatotoxicology Methods
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
T Lymphocytes as Tools in Diagnostics and Immunotoxicology
This book summarizes the state-of-the art in the development of T cell-based in vitro assays, which offer useful tools for hazard identification, risk assessment and improvement of diagnostics. It will be of interest to scientists, the chemical and pharmaceutical industry, and regulators involved in the replacement of animal testing methods. The identification of hazardous chemicals and drugs is essential to ensuring human health. The ban on animal testing for the cosmetics industry since 2009 and international efforts to reduce and replace animal testing in research and immunotoxicology call for alternative in vitro methods. The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response. Therefore the use of T cells as tools for identifying contact allergens and drugs that may cause health problems is of great interest.
British Moths and Butterflies
A comprehensive guide to Britain's moths and butterflies, packed with Chris Manley's stunning photography.
Textbook of Contact Dermatitis
This third edition is an update on every conceivable aspect of the modern-day management of contact dermatitis. Both irritant and allergic contact dermatitis are covered clearly and comprehensively, special emphasis being given to occupational aspects as well as to prevention, diagnosis and treatment. The Textbook also covers epidemiology, the computerization of patch test data and patient information systems, noninvasive bioengineering measurement techniques, methods of skin testing other than patch testing, the histopathology of both irritant and all ergic contact dermatitis, and subjective reactions.
