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This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
This volume of the IARC Monographs provides evaluations of the consumption of red meat and the consumption of processed meat. Red meat refers to unprocessed mammalian muscle meat (e.g. beef, veal, pork, lamb) including that which may be minced or frozen. Processed meat refers to meat that has been transformed through salting, curing, fermentation, smoking or other processes to enhance flavor or improve preservation. Most processed meats contain pork or beef, but may also contain other meats including poultry and offal (e.g. liver) or meat by-products such as blood. Red meat contains proteins of high biological value, and important micronutrients such as B vitamins, iron (both free iron and h...
This volume of the IARC Monographs provides evaluations of the carcinogenicity of pentachlorophenol, 2,4,6-trichlorophenol, 3,3',4,4'-tetrachloroazobenzene, aldrin, and dieldrin. Pentachlorophenol, aldrin, and dieldrin are classified as persistent organic pollutants under the Stockholm Convention. Pentachlorophenol has been widely used as a wood preservative and insecticide, but its production and use are now restricted. 2,4,6-Trichlorophenol has also been used as a wood preservative and insecticide, and in the synthesis of some fungicides. Aldrin and dieldrin are synthetic organochlorine pesticides used as broad-spectrum soil insecticides for the protection of various food crops, as seed dr...
This volume of the IARC Monographs presents evaluations of the carcinogenic hazard to humans of drinking coffee and very hot beverages including, but not limited to, mate. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays and co-carcinogenicity studies, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of drinking coffee, mate, and very hot beverages. The Working Group assessed more than 1000 observational and experimental studies that investigated the association between cancer at more than 20 sites with drinking coffee, mate, and very hot beverages.
This volume of the IARC Monographs provides evaluations of the carcinogenicity of quinoline, styrene, and styrene-7,8-oxide. Quinoline and styrene are present in air pollution and in tobacco smoke. Quinoline also occurs in the processing of petroleum and shale oil, and is found in groundwater and soil at sites contaminated by coal tar and creosote. Quinoline and styrene are high production volume chemicals. Quinoline is used to produce various drugs and dyes. Styrene is primarily used in the production of polystyrene polymers. Styrene-7,8-oxide is primarily used to produce epoxy resins. Styrene-7,8-oxide is the primary metabolite of styrene in humans. Styrene and styrene-7,8-oxide are found in workplace air, particularly in the reinforced plastics industry and the rubber industry. Exposure to these agents may occur in the general population as well as in various occupational settings. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of environmental or occupational exposure to these agents.
This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture ...
Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine