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Systems Biology for Signaling Networks
System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signal...
The Art of Theoretical Biology
This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision.
Foundations of Theoretical Approaches in Systems Biology
If biology in the 20th century was characterized by an explosion of new technologies and experimental methods, that of the 21st has seen an equally exuberant proliferation of mathematical and computational methods that attempt to systematize and explain the abundance of available data. As we live through the consolidation of a new paradigm where experimental data goes hand in hand with computational analysis, we contemplate the challenge of fusing these two aspects of the new biology into a consistent theoretical framework. Whether systems biology will survive as a field or be washed away by the tides of future fads will ultimately depend on its success to achieve this type of synthesis. The famous quote attributed to Kurt Lewin comes to mind: "there is nothing more practical than a good theory". This book presents a wide assortment of articles on systems biology in an attempt to capture the variety of current methods in systems biology and show how they can help to find answers to the challenges of modern biology.
Analysis of Biological Networks
An introduction to biological networks and methods for their analysis Analysis of Biological Networks is the first book of its kind to provide readers with a comprehensive introduction to the structural analysis of biological networks at the interface of biology and computer science. The book begins with a brief overview of biological networks and graph theory/graph algorithms and goes on to explore: global network properties, network centralities, network motifs, network clustering, Petri nets, signal transduction and gene regulation networks, protein interaction networks, metabolic networks, phylogenetic networks, ecological networks, and correlation networks. Analysis of Biological Networ...
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Handbook of Research on Computational Methodologies in Gene Regulatory Networks
"This book focuses on methods widely used in modeling gene networks including structure discovery, learning, and optimization"--Provided by publisher.
Algorithms - ESA 2007
This book constitutes the refereed proceedings of the 15th Annual European Symposium on Algorithms, ESA 2007, held in Eilat, Israel, in October 2007 in the context of the combined conference ALGO 2007. The 63 revised full papers presented together with abstracts of three invited lectures address all current subjects in algorithmics reaching from design and analysis issues of algorithms over to real-world applications and engineering of algorithms in various fields.
Data Integration in the Life Sciences
This book constitutes the refereed proceedings of the First International Workshop on Data Integration in the Life Sciences, DILS 2004, held in Leipzig, Germany, in March 2004. The 13 revised full papers and 2 revised short papers presented were carefully reviewed and selected from many submissions. The papers are organized in topical sections on scientific and clinical workflows, ontologies and taxonomies, indexing and clustering, integration tools and systems, and integration techniques.
An Introduction to Duplicate Detection
With the ever increasing volume of data, data quality problems abound. Multiple, yet different representations of the same real-world objects in data, duplicates, are one of the most intriguing data quality problems. The effects of such duplicates are detrimental; for instance, bank customers can obtain duplicate identities, inventory levels are monitored incorrectly, catalogs are mailed multiple times to the same household, etc. Automatically detecting duplicates is difficult: First, duplicate representations are usually not identical but slightly differ in their values. Second, in principle all pairs of records should be compared, which is infeasible for large volumes of data. This lecture...
Applications and Theory of Petri Nets 2004
This book constitutes the refereed proceedings of the 25th International Conference on Applications and Theory of Petri Nets, ICATPN 2004, held in Bologna, Italy in June 2004. The 19 revised full regular papers and 5 revised tool presentation papers presented together with 6 invited papers were carefully reviewed and selected from 62 submissions. All current issues on research and development in the area of Petri nets are addressed, in particular concurrent systems design and analysis, modular systems development, formal specification, model validation, model checking, workflow management, flow charts, networking, formal methods in software engineering, etc.
