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Autoimmune Thrombocytopenia
This book provides a concise yet comprehensive summary of the current state of knowledge concerning the pathophysiology, differential diagnosis and treatment options that support day-to-day patient management. It reviews a variety of treatments including TOP-R antagonists, along with Syk inhibitor, which has recently proven to be effective, enabling readers to update and broaden their knowledge of the disease. Covering topics ranging from basic science to clinical practice, Autoimmune Thrombocytopenia will appeal to a wide readership, from medical interns and residents to clinicians and hematologists, offering them a thought-provoking, instructive and informative collection of cutting-edge works. Accordingly, readers will gain an overview of the autoimmune and other causes of the disease, and the book will serve as a foundation for new research directions that further our understanding of the pathophysiology and development of diagnosis and treatment options.p>
Antibody Therapy
This practical manual, written by well-known experts, reviews current indications for the use of IgG concentrates and some other modern immunomodulators and provides fundamental information on present-day immunomodulation in patients (and mice). The book opens by tracing the transition from IgG substitution to IgG immunomodulation and providing expert updates on immunomodulatory indications in autoimmune and inflammatory disorders, including hematologic, neurologic, dermatologic, and other diseases. Basic aspects of IgG concentrates, including methods of production, safety, currently available products, and mechanisms of action, are then discussed. An entire chapter is devoted to the different aspects of immunomodulatory IgG treatment in the bleeding disorder immune thrombocytopenia (ITP). Finally, the transition from polyclonal to monoclonal antibody (mAb) treatment is addressed in detail, covering mAb development, methods, mechanisms of action, adverse effects, and more. Particular attention is paid to the example of anti-CD20 (B-cell) antibody.
Nathan and Oski's Hematology of Infancy and Childhood E-Book
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you’ll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski’s Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the ful...
Pediatric Hematology
Pediatric Hematology is a comprehensive and succinct referenced text on the diagnosis and treatment of blood diseases in childhood. It provides a ready source of reference for all the conditions likely to be encountered in day-to-day clinical practice. For each condition, the authors give helpful advice on differential diagnoses and clinical management. This third edition has been extensively updated throughout, in light of recent developments in this rapidly advancing area of medicine. A well established textbook on the diagnosis and treatment of blood disorders in childhood A balanced and cutting edge referenced text on all aspects of diagnosis and treatment Easy to use, practically organized, with essential aspects of biology included within each chapter International editorial and contributor team—representing a wide geographical and chronological range Whether you are an established sub-specialist in pediatric hematology/oncology, a pediatrician, a trainee or nursing specialist, this book will answer all your questions about benign and malignant disorders of the blood in children and young adults.
Benign Hematologic Disorders in Children
This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell disorders, and coagulation disorders. The sixth and seventh sections discuss neonatal hematology and bone marrow failure syndrome. The eighth section reviews supportive care, while the final section covers miscellaneous subjects including pediatric vascular anomalies and complement dysregulation syndromes. Written by experts in the field, Benign Hematologic Disorders in Children: A Clinical Guide is a valuable resource for clinicians and practitioners who treat children afflicted with these disorders.
Nathan and Oski's Hematology of Infancy and Childhood
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you'll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski's Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full ra...
Pediatric Bleeding Disorders
This clinical casebook provides a concise, state-of-the-art review of pediatric bleeding disorders. Presented in a case-based format, each case presents a different variant of bleeding disorder, illustrates the etiology, pathology, genetics, diagnosis, and management of the disorder, and offers clinical pearls. Disorders covered include hemophilia A and B, rare factor deficiencies, von Willebrand disease, immune thrombocytopenia purpura, and platelet dysfunctions. Written by experts in the field, Pediatric Bleeding Disorders: A Clinical Casebook is a valuable resource for clinicians and practitioners treating patients with challenging coagulation issues.
Controversies in Pediatric and Adolescent Hematology
Hematological disorders in children and adolescents pose a wide range of management challenges and treatment dilemmas. In this book an internationally acclaimed panel of authors, each chosen for expertise in their field, have produced a state-of-the-art collection of review articles focusing on the very latest advances and controversies in the management of pediatric and adolescent hematological problems. The whole range of benign and malignant, congenital and acquired, acute and chronic conditions is discussed in detail. Individual chapters cover hematologic problems on the pediatric intensive care unit, treatments for iron deficiency and ITP; advances in stem cell transplantation, gene therapy, novel pharmaceutics and molecular diagnostics, as well as transition from child to adult are also explored. Providing an up-to-date look at both specific hematologic disorders in the pediatric and adolescent population and also hematologic problems that arise in association with systemic disease, this book is essential reading not only for pediatric and adult hematologists but also for pediatricians, pediatric or hematologic specialist nurse practitioners and pediatric pharmacologists.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Wintrobe's Clinical Hematology
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
