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Interstitial Lung Disease, Fourth Edition is a complete publication of interstitial lung diseases and includes clinical, pathologic, radiologic, and physiologic evaluation of the patient with ILD. It provides a basic pathobiology and a complete description of individual disease entities. The book covers a wide array of disorders - sarcoidosis, asbestosis, hypersensitivity pneumonitis, drug-induced lung disease, connective tissue disease, and pulmonary vasculitis, to name but a few. This new edition also features an examination of future potential therapies for interstitial lung disease. Interstitial Lung Disease is divided into three sections. The Clinical Approach section provides the basis...
This book discusses basic and clinical aspects of selected topics in interstitial lung disease and the pathogenic mechanisms of pulmonary fibrosis. Topics include the pathogenesis of interstitial fibrosis from the initial injury to the excessive accumulation of collagens in lung parenchyma; detailed analysis of the role of fibroblasts, mast cells and growth factors in the induction of fibrogenesis; collagens, collagenases, and proteoglycans; and hypersensitivity, pneumonitis and asbestosis. Other topics include morphological aspects, including molecular biology techniques, imaging methods, functional respiratory tests, and pulmonary arterial hypertension; and sleep disorders in patients with ILD. This book provides important information for physicians, surgeons, pulmonary researchers, molecular pathologists, biomedical researchers and students, and others interested in interstitial lung disease.
Primary sexual traits, those structures and processes directly involved in reproduction, are some of the most diverse, specialized, and bizarre in the animal kingdom. Moreover, reproductive traits are often species-specific, suggesting that they evolved very rapidly. This diversity, long the province of taxonomists, has recently attracted broader interest from evolutionary biologists, especially those interested in sexual selection and the evolution of reproductive strategies. Primary sexual characters were long assumed to be the product of natural selection, exclusively. A recent alternative suggests that sexual selection explains much of the diversity of “primary” sexual characters. A ...
Explored in this book are the effect of environmental changes on most animals (especially poiilothermic animals) at two levels, the proximate process, where environmental changes affect their development, and the ultimate process level, where natural selection acts on the changes undergone during the proximate process. It reexamines neo-Lamarckism in light of 20th century biology and shows it as a major pattern of evolution. The book also focuses on how environmental factors influence endocrine balances that in turn affect gene regulation.
Tackling one of the most difficult and delicate of the evolutionary questions, this challenging book summarizes the more recent results in phylogenetics and developmental biology that address the evolution of key innovations in metazoans. Divided into three sections, the first considers the phylogenetic issues involving this area of the tree of lif
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Bringing together the viewpoints of leading experts in taxonomy, ecology and biogeography of different taxa, this book synthesises discussion surrounding the so-called 'everything is everywhere' hypothesis. It addresses the processes that generate spatial patterns of diversity and biogeography in organisms that can potentially be cosmopolitan. The contributors discuss questions such as: are microorganisms (e.g. prokaryotes, protists, algae, yeast and microscopic fungi, plants and animals) really cosmopolitan in their distribution? What are the biological properties that allow such potential distribution? Are there processes that would limit their distribution? Are microorganisms intrinsically different from macroscopic ones? What can microorganisms tell us about the generalities of biogeography? Can they be used for experimental biogeography? Written for graduate students and academic researchers, the book promotes a more complete understanding of the spatial patterns and the general processes in biogeography.