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Covers the history of twelve important diseases and addresses public health responses and societal upheavals. Chronicles the ways disease outbreaks shaped traditions and institutions of Western civilization. Explains the effects, causes, and outcomes from past epidemics. Describes a dozen diseases to show how disease control either was achieved or failed. Makes clear the interrelationship between diseases and history. Presents material in a compelling, clear, and jargon-free prose for a wide audience. Provides a picture of the best practices for dealing with disease outbreaks.
The Power of Plagues presents a rogues' gallery of epidemic- causing microorganisms placed in the context of world history. Author Irwin W. Sherman introduces the microbes that caused these epidemics and the people who sought (and still seek) to understand how diseases and epidemics are managed. What makes this book especially fascinating are the many threads that Sherman weaves together as he explains how plagues past and present have shaped the outcome of wars and altered the course of medicine, religion, education, feudalism, and science. Cholera gave birth to the field of epidemiology. The bubonic plague epidemic that began in 1346 led to the formation of universities in cities far from ...
Chronicling a 100-year quest, this book tells the fascinating story of the hunt for the still-elusive malaria vaccine. Sherman captures the controversies, missteps, stolen ideas, and clashes of ego as researchers around the world compete to develop the first successful malaria vaccine.
Drugs are used in the diagnosis, alleviation, treatment, prevention or cure of disease. This is a book about drugs, how they came to be, and how they exert their ‘magic’. Today we have drugs to protect against infectious diseases, to alleviate aches and pains, to allow new organs to replace the old, and for brain functions to be modified. Yet, for the most part the manner by which drugs are developed and by whom remains a mystery. Drugs are more than just a pill or liquid and some have markedly altered history. The author has selected a few drugs – highlights representing milestones affecting our well-being and influencers of social change. The stories told are dramatic and include spectacular successes and dismal failures. And the people about whom these stories are told are both saints and sinners – selfless and conniving – bold and mercurial and shy and retiring loner. The drugs themselves mirror the diversity of their origin stories and the author assembles all sides of these fascinating stories.
Malaria is one of the most common infectious diseases and an enormous public health problem. Each year it causes disease in approximately 650 million people and kills between 1 and 3 million, most of them young children in Sub-Saharan Africa. This book provides an overview of the research that has been done in malaria biochemistry in the quest to find a cure. It discusses how our understanding has helped us to develop better diagnostics and novel chemotherapies. Researchers will find having all of this information in one volume, annotated with personal reflections from a leader in the field, invaluable given the big push being made on various fronts to use the latest drug discovery tools to attack malaria and other developing country diseases. - Reviews the past 100 years of malaria biochemistry research providing researchers with an overview of the investigations that have been undertaken in this field - Chronicles both biochemical successes and failures
The year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequences were a result of the Plasmodium falciparum Genome Project. This book covers in detail the biology of malaria parasites and the mosquitoes that transmit the disease, how the Genome Project came into being, the people who created it, and the cadre of scientists who are attempting to see the promise of the Project realized. The promise was: a more complete understanding of the genes of the parasite (and its vector) would provide a rational basis for the development of antimalarial drugs and vaccin...
A clear, concise discourse of 300 years of malarial drug research. Serves as a resource for microbiologists, parasitologists, pharmacologists, medicinal chemists, biochemists, physicians, and drug researchers.
At the outset of the twentieth century, malaria was Italy’s major public health problem. It was the cause of low productivity, poverty, and economic backwardness, while it also stunted literacy, limited political participation, and undermined the army. In this book Frank Snowden recounts how Italy became the world center for the development of malariology as a medical discipline and launched the first national campaign to eradicate the disease. Snowden traces the early advances, the setbacks of world wars and Fascist dictatorship, and the final victory against malaria after World War II. He shows how the medical and teaching professions helped educate people in their own self-defense and in the process expanded trade unionism, women’s consciousness, and civil liberties. He also discusses the antimalarial effort under Mussolini’s regime and reveals the shocking details of the German army’s intentional release of malaria among Italian civilians—the first and only known example of bioterror in twentieth-century Europe. Comprehensive and enlightening, this history offers important lessons for today’s global malaria emergency.
In the battle between humans and microbes, knowledge may be not only the best weapon but also the best defense. Pulling contributions from 34 experts into a unified presentation, Disinfection and Decontamination: Principles, Applications, and Related Issues provides coverage that is both sophisticated and practical. The book reviews the fund
This popular college textbook presents the substance of modern biology with special focus on human biology and contemporary topics.