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Magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques have opened new doors for examining biological tissues in vivo. By combining sensitization to diffusion using magnetic field gradients with a variety of imaging and localization schemes, diffusion-weighted MRI and diffusion-weighted MRS allow investigating translational diffusion of endogenous molecules, such as water or metabolites, in biological tissues, most commonly the brain but also other organs such as the prostate. The typical voxel resolution of MRI or MRS is in the millimeter to centimeter range, much lower than the cellular scale. However, as molecules are typically diffusing over just a few µm during the duration...
Computerized medical imaging and image analysis have been the central focus in diagnostic radiology. They provide revolutionarizing tools for visualization of physiology as well as the understanding and quantitative measurement of physiological parameters. This book provides a unique depth of knowledge from the principles to recent advanced methods in medical imaging instrumentation and techniques as well as multidimensional image analysis and classification methods for research, education and applications in computer-aided diagnostic radiology. Internationally renowned researchers and experts in their respective areas provide detailed description of the basic foundation as well as the most recent developments in medical imaging. This book helps readers to understand theoretical and advanced concepts for important research and clinical applications.
The Handbook consists of four major sections. Each section is introduced by a main article: Theories of Emotion – General Aspects Perspectives in Communication Theory, Semiotics, and Linguistics Perspectives on Language and Emotion in Cultural Studies Interdisciplinary and Applied Perspectives The first section presents interdisciplinary emotion theories relevant for the field of language and communication research, including the history of emotion research. The second section focuses on the full range of emotion-related aspects in linguistics, semiotics, and communication theories. The next section focuses on cultural studies and language and emotion; emotions in arts and literature, as w...
Topic Editor Prof. James Duffin contributed to the development of an automated end-tidal targeting device, RespirActTM and is employed by Thornhill Medical Inc. (Toronto, Canada). RespirActTM is currently a non-commercial research tool assembled and made available by TMI to research institutions to enable CVR studies. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Brain imaging has seen considerable advances over the recent years. Both developments and validation of advanced image acquisition techniques as well as post-processing and analyses pipelines contribute to contemporary imaging, including parallel imaging, (semi-)automated segmentation, generation of synthetic images, and application of machine learning and radiomics. Multi-modal approaches using structural, metabolic, and functional imaging are emerging to build a framework for a better understanding of anatomical features and physiological processes of the brain. This Research Topic intends to cover a broad theme, welcoming contributions spanning across the fields of (neuro)radiology, medic...
This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscl...