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Toward Anti-Adhesion Therapy for Microbial Diseases
The emergence of pathogens resistant to conventional antimicrobial agents has forced us to intensify the efforts in search for new approaches to prevent infectious diseases. Such a direction was indicated in studies over the last two decades showing that adhesion of pathogens, primarily via glycoconjugate or protein receptors of the host tissue, is crucial for the infectious process. Moreover, it was found that infection can be prevented by blocking adhesion of the pathogen to mucosal surfaces of the host. The various aspects of interference with the process of microbial adhesion as a way of preventing diseases were the subject of the Bat-Sheva Seminar, "Towards Anti-Adhesion Therapy of Micr...
Mycoplasma Cell Membranes
The mycoplasmas, a trivial name used to denote organisms included in the class Mollicutes, are a group of prokaryotic organisms comprising more than 120 species distinguished from ordinary bacteria by their small size and the total lack of cell walls. The absence of a cell wall in mycoplasmas is a characteristic of outstanding importance to which the mycoplasmas owe many of their pecu liarities, for example, their morphological instability, osmotic sensitivity, unique ion pumping systems, resistance to antibiotics that interfere with cell wall bio synthesis, and susceptibility to lysis by detergents and alcohols. The fact that the mycoplasma cells contain only one membrane type, the plasma m...
Rapid Diagnosis of Mycoplasmas
This compendium is the result of the FEMS Workshop on "Rapid Diagnosis of Mycoplasmas" which I organized and which took place in Jerusalem, Israel, August 11-23, 1991. The first week's sessions were held at a resort on the outskirts of Jerusalem and consisted of lectures and discussions. This part was modelled along the lines of the Gordon Conference in the USA, i.e., in an intimate atmo sphere in which everyone could mix and exchange ideas, and was very benefi cial. About 100 scientists from around the world attended the first week. Dur ing the first week, the biology, molecular biology and pathophysiology of myco plasmas, as well as all the main diagnostic methods were covered, including b...
Molecular and Diagnostic Procedures in Mycoplasmology
This book and its companion, Volume II, concentrate on new procedures--especially those based on the new molecular methodology--developed within the past decade. This volume outlines the approaches, techniques, and procedures applied to cell and molecular biology studies of mycoplasmas. Volume II deals with the new genetic and immunological tools applied to the diagnosis of mycoplasma infections of humans, animals, plants, insects, and all cultures, with particular emphasis on the association of mycoplasmas with the activation of AIDS.Key Features* Cultivation and morphology* Genome characterization and genetics* Membrane characterization* Cell metabolism* Taxonomy and phylogeny* Pathogenicity
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Meir Kahane
The life and politics of an American Jewish activist who preached radical and violent means to Jewish survival Meir Kahane came of age amid the radical politics of the counterculture, becoming a militant voice of protest against Jewish liberalism. Kahane founded the Jewish Defense League in 1968, declaring that Jews must protect themselves by any means necessary. He immigrated to Israel in 1971, where he founded KACH, an ultranationalist and racist political party. He would die by assassination in 1990. Shaul Magid provides an in-depth look at this controversial figure, showing how the postwar American experience shaped his life and political thought. Magid sheds new light on Kahane’s radi...
