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How do we forget? Why do we need to forget? This book intends to answer to these and other questions. It aims to demonstrate that each one is who it is due to their own memories. Thus, distinguish between the information we should keep from those we should forget is an difficult art. In this book, the author discusses about the different types of memory, the main types of forgetting (avoidance, extinction and repression), their brain areas and their mechanisms. In this sense, the art of forgetting, or the art of do not saturate our memory mechanisms, is something innate, that benefits us anonymously, keeping us from sinking amidst our own memories. The essays that compose this book go through several aspects, since individuals to societies' memory. By the end of the book, the reader will be able to understand that we forget to be able to think, to live and to survive.
Esta obra reflete 40 anos dedicados ao estudo da memória, enfatizando seus aspectos biológicos e concentrando-se naqueles processos melhor demonstrados e sobre os quais existe consenso. Também serviram como base as perguntas mais habituais formuladas ao autor, Iván Izquierdo, por jornalistas ou pelo público em geral, especializado ou não, em palestras por ele proferidas.
The seventh volume of The History of Neuroscience in Autobiography is a collection of autobiographical essays by distinguished senior neuroscientists in which they recount the events that shaped their lives and identify the mentors and colleagues who inspired them. The narratives provides a human dimension to the world of scientific research.
Deals primarily with the role of emotions in the mechanisms of memory. A compilation of the lectures given at a course conducted at the International School of Biocybernetics.
"This monograph is based upon papers and discussion from the technical review on the medicinal chemistry and molecular pharmacology of opioid peptides and the opiates which took place on September 4-6, 1984, at Bethesda, Maryland. The meeting was sponsored by the Office of Science and the Division of Preclinical Research, National Institute on Drug Abuse. The papers on molecular pharmacology, biosynthesis, and analysis of opioid peptides are presented in this volume. Those on the medical chemistry of opioid peptides appear in NIDA Research Monograph 69" [entitled Opioid peptides : medicinal chemistry] -- page iv.
The purpose of this book is to describe the memory system of the brain, taking into account all the levels of neural organization: molecule, cell, small network, and anatomical circuit. This synthetic approach is necessary for determining the real mechanisms among the potential ones, that is the neural bases of learning and memory in intact organisms functioning under normal conditions. For this purpose, data from molecular, cellular and behavioral neurobiology, neuropsychology, animal and human psychology, and neural modellization are comprehensively reviewed by leading specialists and brought together in an original synthesis.
Research in the field of histamine receptors over the past 100 years went hand-in-hand with the development of modern pharmacology. Advances in histamine research led by outstanding scientists was so incisive that the clinical approach to treat allergies and gastrointestinal ailments was revolutionized. The pharmacological treatment of peptic ulcer and gastroesophageal reflux was indeed a revolution, as it ended the surgical intervention. Interest in histamine pharmacology was resurrected by the discovery of another histamine receptor, number 4, using genomics-based reverse pharmacological approaches for screening orphan GPCRs. This receptor is preferentially expressed by immune cells and it...
Whereas the past few years have repeatedly been referred to as the “era of biotechnology”, most recently the impression has emerged that at least the same degree of attention is being paid to the latest developments in the field of neurosciences. It has now become nearly impossible to maintain an overview of the number of research projects dealing with the functionality of the brain – for example concerning its organizational structure – or projects dealing with the topics of legal responsibility, brain-computer interface applications, neuromarketing, lie detection or mind reading. These procedures are connected to a number of legal questions concerning the framework conditions of re...
The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.
The decade of the brain has brought us a few steps closer to some of the key questions in neuroscience. The complexity of memory is seen on the systems and cellular level, and different types of memory are implemented in several cellular changes that can interact, or work independently. From Messengers to Molecules: Memories are Made of These, follows the arguments from different research teams for their particular area of expertise. All chapters are written to stand-alone and provide an up-to-date introduction to the topic for both specialists and novices alike. As a result, a comprehensive compendium covering cellular mechanisms contributing to memory formation in an unusual breadth has emerged. This books will be of interest to researchers working on the pharmacology, physiology and genetics of memory formation, clinicians memory disorders, industry and students in advanced courses in Neuroscience or Pharmacology.