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Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Graduate Education in the Chemical Sciences
Graduate Education in the Chemical Sciences is a summary of the December 1999 workshop, "Graduate Education in the Chemical Sciences: Issues for the 21st Century." This workshop discussed the various features of graduate education in chemical science and technology. Using case histories and their individual experiences, speakers examined the current status of graduate education in the chemical sciences, identified problems and opportunities, and discussed possible strategies for improving the system. The discussion was oriented toward the goal of generating graduates who are well prepared to advance the chemical sciences in academia, government, and industry in the next 5 to 10 years.
Catalytic Asymmetric Synthesis
Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.
Fluorine in Medicinal Chemistry and Chemical Biology
The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospect...
New Methodologies and Techniques for a Sustainable Organic Chemistry
Chemical industries have to face the challenge of finding adequate processes to produce large quantities of new products, while at the same time decreasing both the impact on the environment and the risk of disaster. This book addresses this challenge. It discusses the problems of environmentally benign organic processes on an interdisciplinary approach. The book features experts in selective catalysis, development of new reagents and methods who present their recent results.
Advances in Medicinal Chemistry
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment ...
Aspects of Homogeneous Catalysis
In recent years, the liquid phase oxidation of organic substrates using transition metal compounds as catalysts has become a profitable means of obtaining industrially important chemicals. Millions of tons of valuable petrochemicals are produced in this manner annually [1]. Typical examples of such processes are the production of vinyl acetate or acetaldehyde via the Wacker process, equations (1) and (2); the Mid Century process for the oxidation of methyl aromatics, such as p-xylene to tereph thalic acid, equation (3); and the production of propylene oxide from propylene using alkyl hydroperoxides, equation (4). PdCI , CuCI 2 2 (1) CH2 = CH2 + 1/2 O2 -H 0 ~ CH3CHO 2 (2) Co(OAcjz ~ (3) (4) T...
Advances in Asymmetric Synthesis
Advances in Asymmetric Synthesis
