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The outstanding contributions to this volume are designed to shed light on some fields of cell biology and cellular pathology, including newly observed phenomena of cell-cell interactions, which might be applicable in studying the pathological process of atherosclerosis. The topics included cover: lipoproteins and lipoprotein receptors; growth factors; endocytosis and exocytosis; ONC Genes and proliferative disease; white blood cells; prostaglandins and leukotrienes; and the biology of smooth muscle and endothelium. The volume provides a complete summary of the most important developments in the field with great impact for arteriosclerosis research.
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This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis. In addition, complement is often involved in adverse immune reactions to biomaterials, cell and organ transplants or drug delivery systems. Although the complement cascade with its close to 50 extrac...
Genetic disorders have emerged as a prominent cause of morbidity and mor tality among infants and adults. As many as 10% to 20% of hospital admis sions and at least 10% of the mortality in this age group are due to inherited diseases. There are at least two factors that have brought genetic disorders into the forefront of pediatrics. One is a great reduction in childhood mortality due to infections and nutritional deficiency states, and the other is the rapid progress made in the identification of genetic defects. Amniocentesis, chorionic villus sampling, and recombinant DNA technology have already had a tremendous impact on the practice of medicine. This is why the first two chapters of thi...
The field of interventional cardiology and interventional vascular medicine now comprises the dominant diagnostic and therapeutic field within cardiovascular medicine, and continues to grow in terms of patients managed and physicians trained. The Textbook of Cardiovascular Intervention is intended to provide a modern, comprehensive and practical text on interventional cardiology for the current, rapidly evolving practice environment. It is written by a group of worldwide experts in the field and will appeal to fellows, residents and physicians in cardiology, interventional cardiology, cardiothoracic and vascular surgery, vascular and endovascular medicine, neurointerventional radiology and surgery, emergency medicine and intensive care.
Recent advances in power electronics greatly benefit the multidisciplinary field of modern ultrasonics. More powerful, compact, and versatile electronic chips and software enable new computer-based devices for real-time data capture, storage, analysis, and display and advance the science and technology employed in commercial systems and applications of ultrasound. Reviewing the scientific basis behind these improvements, Ultrasonics: Fundamentals, Technologies, and Applications, Third Edition discusses them in detail, with new and additional figures and references, offering a completely revised and expanded examination of the state of modern ultrasonics. This new edition of a bestselling ind...
Strength of Metals and Alloys, Volume 3 (ICSMA 7) presents the proceedings of the 7th International Conference on the Strength of Metals and Alloys held in Montreal, Canada on August 12-16, 1985. The book includes papers on the work hardening of face-centered cubic single crystals; precipitation hardening; and microstructure evolution and flow stress during hot working. The text also covers papers on microstructure evolution and flow stress during hot working; the prediction of deformation textures in cubic metals; creep of copper-base shape memory alloys; and flow behavior of nickel-base superalloys at isothermal forging temperatures and strain rates. Grain refinement by recrystallization hot-rolling to achieve high strength and notch toughness in microalloyed steel plate; as well as the influence of mean stress on fatigue strength of TI-6A1-4V are also encompassed. The book further includes papers on the comparative mechanical properties of human bones; the effect of precipitation hardening on the decomposition of the solid solution in 7075 alloy during quenching; and the mechanical properties of stable and unstable austenitic stainless steels.
Advances in Immunology