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In Neural Organization, Arbib, Érdi, and Szentágothai integrate structural, functional, and dynamical approaches to the interaction of brain models and neurobiologcal experiments. In Neural Organization, Arbib, Érdi, and Szentágothai integrate structural, functional, and dynamical approaches to the interaction of brain models and neurobiologcal experiments. Both structure-based "bottom-up" and function- based "top-down" models offer coherent concepts by which to evaluate the experimental data. The goal of this book is to point out the advantages of a multidisciplinary, multistrategied approach to the brain. Part I of Neural Organization provides a detailed introduction to each of the thr...
I - Analysis and Modeling Tools and Techniques.- Section 1: Analysis.- Assembly Connectivity and Activity: Methods, Results, Interpretations.- Visualization of Cortical Connections With Voltage Sensitive Dyes.- Channels, Coupling, and Synchronized Rhythmic Bursting Activity.- Sparse-stimulation and Wiener Kernels.- Quantitative Search for Stimulus-Specific Patterns in the Human Electroencephalogram (EEG) During a Somatosensory Task.- Section 2: Modeling.- Functional Insights About Synaptic Inputs to Dendrites.- Dendritic Control of Hebbian Computations.- Low Threshold Spikes and Rhythmic Oscil.
Brain Reflexes
This book encompasses basic and clinical reports on the cerebellum and its primary atrophic disorders, the cerebellar degenerations. Rapid progress has been made in undestanding the organization and function of the cerebellum at the neuronal, synaptic, and molecular level. Of particular importance has been the identification of the chemical transmitters utilized by the cer ebellar cellular systems. More than any other brain region, the cerebellum utilizes amino acids as its main excitatory and inhibitory neurotransmitters. Excitatory amino acid transmitters, in addition to serving neuronal com munication, may also mediate trophic and toxic effects, and as such, they may playa role in neurode...
I must thank my friend, Professor HANS WEBER, for being, as it were, the prime mover in causing this book to be written. He persuaded me in 1960 to contribute a review to the Ergebnisse der Physiologie. As originally planned, it was to be relatively short. However, the interest and scope of the whole subject of synapses stimulated me to write a much more comprehensive and extensive account. I was not even then satisfied, particularly as so many new and attractive investigations and ideas were being evolved during and after the writing of this review; and during the writing of this book most interesting developments are occurring in so many centres of research. Through the kind cooperation of...
Vitamins and Hormones
The growth of neurochemistry, molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systematic summa tion, and, of course, no one author can cope. Thus invitations for contributions were given to various experts in areas which are under active investigation, of current neurological interest, and pregnant. Although this project is relatively comprehensive, by dint of size, other topics might have been included; the selection was solely my responsibility. I believe systematic summation a v...
The author makes a unique contribution to the field by discussing the history and philosophy of the neurosciences, and then developing critical approaches which integrate techniques, theory, and ethics. Taken as a whole, Jacobson's work will provide a coherent and humane framework for future research programs. The paperback edition of this highly successful text, first published in 1993, is now available! The author brings the ethics of neuroscience into a closer relationship with empirical research. Covering the field's history, philosophy, theories, and techniques, this volume provides the necessary moral and ethical framework to evaluate neuroscience research.
This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice. Organized by the distinctive ataxia disorders, their pathogenesis, and management-facilitating quick and efficient diagnoses! Providing complementary sections on the anatomy of the spinocerebellar system, its normal function, and a history of ataxia research and management, the Handbook of Ataxia Disorders clarifies the impact of identifying the molecular causes of ataxia offers in-depth analysis of dominant and recessive and nonheredi...
Dr. Shakhnovich brought out the original Russian edition of this work in 1974. Fully half of that book was concerned with his own studies of eye movements. These included observations on patients with neuromuscular disorders that produced unique oculomotor deficits. Other anomalies of eye motility resulted from local changes in cerebral and cerebellar blood flow and the effects of surgical intervention for aneurisms and brain tumors. Supplementary experi ments included the probing of single units in the motor and visual brain areas of rabbits. Still other studies were done on normal human eye movements with the aid of the Yarbus "cap" attachment to the cornea of the eye. A major aim of the o...