Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Our NHS
An engaging, inclusive history of the NHS, exploring its surprising survival—and the people who have kept it running In recent decades, a wave of appreciation for the NHS has swept across the UK. Britons have clapped for frontline workers and championed the service as a distinctive national achievement. All this has happened in the face of ideological opposition, marketization, and workforce crises. But how did the NHS become what it is today? In this wide-ranging history, Andrew Seaton examines the full story of the NHS. He traces how the service has changed and adapted, bringing together the experiences of patients, staff from Britain and abroad, and the service’s wider supporters and opponents. He explains not only why it survived the neoliberalism of the late twentieth century but also how it became a key marker of national identity. Seaton emphasizes the resilience of the NHS—perpetually “in crisis” and yet perennially enduring—as well as the political values it embodies and the work of those who have tirelessly kept it afloat.
Two Faces of Evil: Cancer and Neurodegeneration
Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of signal transduction processes. Failures in these complex communication pathways result in instability leading to disease. Cancer represents a state of imbalance caused by an excess of cell proliferation. In contrast, neurodegeneration is a consequence of excessive cell loss in the nervous system. Both of these disorders exhort profound tolls on humanity and they have been subject to a great deal of research designed to ameliorate this suffering. For the most part, the topics have been viewed as distinct and rarely do opportunities arise for transdisciplinary discussions among experts in both fields. However, cancer and neurodegeneration represent yin-yang counterpoints in the regulation of cell growth, and it is reasonable to hypothesize that key regulatory events mediated by oncogenes and tumor suppressor genes in cancer may also affect neurodegenerative processes
Proceedings of the XIV Symposium Neuroradiologicum
Every 4 years, neuroradiologists from around the world meet at an international congress in order to discuss the state of their art.
Metallic, Magnetic, and Carbon-Based Nanomaterials
A comprehensive guide to an explosively popular and transformative technology Nanotechnology has revolutionized the manipulation of matter at the molecular level, with extraordinary consequences for a huge range of technological and scientific fields. Metallic, magnetic and carbon-based nanomaterials have been at the forefront of this revolution, with their impact felt especially strongly in biomedical industries. The future of drug delivery, imaging, diagnostics, and more will be transformed by nanotechnology and its ever-growing applications. Metallic, Magnetic and Carbon-Based Nanomaterials offers a comprehensive introduction to these materials and their recent developments. Beginning wit...
Neuronal Cell Death
This volume covers comprehensive methods on ways to assess structural and ultrastructural changes in the mitochondria, cytoskeleton, and microglia using state-of-the-art microscopy techniques including super-resolution imaging, electron microscopy, and ultra-high field MRI. The chapters in this book cover topics such as analysis of neurodegeneration in the post-mortem characterization of preclinical animal models, in vivo modeling in cell death in different model systems and brain organoids, single cell clonal analysis using Mosaic Analysis with Double Markers in genetic mouse models, and genome and proteomic methods for analysis of mRNA dynamics and quantitation of targeted peptides. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Neuronal Cell Death: Methods and Protocols is a valuable resource for any scientist and researcher interested in learning more about this developing field.
Polyglutamine Disorders
This book provides a cutting-edge review of polyglutamine disorders. It primarily focuses on two main aspects: (1) the mechanisms underlying the pathologies’ development and progression, and (2) the therapeutic strategies that are currently being explored to stop or delay disease progression. Polyglutamine (polyQ) disorders are a group of inherited neurodegenerative diseases with a fatal outcome that are caused by an abnormal expansion of a coding trinucleotide repeat (CAG), which is then translated in an abnormal protein with an elongated glutamine tract (Q). To date, nine polyQ disorders have been identified and described: dentatorubral-pallidoluysian atrophy (DRPLA); Huntington’s dise...
Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye
Undoubtedly, Drosophila melanogaster, fruit fly, has proved to be one of the most popular invertebrate model organisms, and the work horse for modern day biologists. Drosophila, a highly versatile model with a genetic legacy of more than a century, provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology focuses on how does a multi-cellular organism develop from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question, and led to other questions, such as the role of various genetics and cell bi...
Journal of the Medical Association of Thailand
The journal of Medical Association of Thailand publishs original and review articles including case report that relate to the study or research on diseases, epidemiology, drug or vaccine that have the influence on clinical course, treatment and prevention of human illness
Advances in Production Management Systems. Artificial Intelligence for Sustainable and Resilient Production Systems
The five-volume set IFIP AICT 630, 631, 632, 633, and 634 constitutes the refereed proceedings of the International IFIP WG 5.7 Conference on Advances in Production Management Systems, APMS 2021, held in Nantes, France, in September 2021.* The 378 papers presented were carefully reviewed and selected from 529 submissions. They discuss artificial intelligence techniques, decision aid and new and renewed paradigms for sustainable and resilient production systems at four-wall factory and value chain levels. The papers are organized in the following topical sections: Part I: artificial intelligence based optimization techniques for demand-driven manufacturing; hybrid approaches for production pl...
