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Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An overview of the four major pathways of homologous recombinational repair is followed by a description of the several mechanisms of nonhomologous end-joining. Designed as a textbook for advanced undergraduate and graduate students with a molecular biology and genetics background, researchers and practitioners, especially in cancer biology, will also appreciate the book as a reference.
This collection of essays grew out of a symposium commemorating the 250th anniversary of the founding of Georgia. The contributors are authorities in their respective fields and their efforts represent not only the fruits of long careers but also the observations and insights of some of the most promising young scholars. Forty Years of Diversity sheds new light on the social, political, religious, and ethnic diversity of colonial Georgia.
James Habersham was an early American success story. After arriving in Savannah in 1738, he failed in his efforts to wrest a living from the Georgia wilderness and lived his first year at public expense. Then, by dint of his own efforts and through the connections he forged, Habersham emerged as one of the colony's most influential and prosperous citizens, making his name as a planter, merchant, evangelist, and political leader. The third wealthiest person in the colony at the time of his death in 1775, Habersham had a public career that included service as the secretary of Georgia, president of the King's council, and acting Governor. But Habersham's story is more than biography. It also pr...
Lines in the Sandis Timothy Lockley’s nuanced look at the interaction between nonslaveholding whites and African Americans in lowcountry Georgia from the introduction of slavery in the state to the beginning of the Civil War. The study focuses on poor whites living in a society where they were dominated politically and economically by a planter elite and outnumbered by slaves. Lockley argues that the division between nonslaveholding whites and African Americans was not fixed or insurmountable. Pulling evidence from travel accounts, slave narratives, newspapers, and court documents, he reveals that these groups formed myriad kinds of relationships, sometimes out of mutual affection, sometimes for mutual advantage, but always in spite of the disapproving authority of the planter class. Lockley has synthesized an impressive amount of material to create a rich social history that illuminates the lives of both blacks and whites. His abundant detail and clear narrative style make this first book-length examination of a complicated and overlooked topic both fascinating and accessible.
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Reprint of the original, first published in 1877.
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DIVHow did colonial Georgia, an economic backwater in its early days, make its way into the burgeoning Caribbean and Atlantic economies where trade spilled over national boundaries, merchants operated in multiple markets, and the transport of enslaved Africans bound together four continents? In On the Rim of the Caribbean, Paul M. Pressly interprets Georgia's place in the Atlantic world in light of recent work in transnational and economic history. He considers how a tiny elite of newly arrived merchants, adapting to local culture but loyal to a larger vision of the British empire, led the colony into overseas trade. From this perspective, Pressly examines the ways in which Georgia came to s...