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Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understa...
Using real-world data case studies, this innovative and accessible textbook introduces an actionable framework for conducting trustworthy data science. Most textbooks present data science as a linear analytic process involving a set of statistical and computational techniques without accounting for the challenges intrinsic to real-world applications. Veridical Data Science, by contrast, embraces the reality that most projects begin with an ambiguous domain question and messy data; it acknowledges that datasets are mere approximations of reality while analyses are mental constructs. Bin Yu and Rebecca Barter employ the innovative Predictability, Computability, and Stability (PCS) framework to...
This book presents recent developments in multivariate and robust statistical methods. Featuring contributions by leading experts in the field it covers various topics, including multivariate and high-dimensional methods, time series, graphical models, robust estimation, supervised learning and normal extremes. It will appeal to statistics and data science researchers, PhD students and practitioners who are interested in modern multivariate and robust statistics. The book is dedicated to David E. Tyler on the occasion of his pending retirement and also includes a review contribution on the popular Tyler’s shape matrix.
This book constitutes the proceedings of the 23rd International Conference on Information Processing in Medical Imaging, IPMI 2013, held in Asilomar in June/July 2013. The 26 full papers and 38 poster papers presented in this volume were carefully reviewed and selected from 199 submissions. The papers are organized in topical sections on connectivity, groupwise registration, neuro segmentation, statistical analysis, dynamic imaging, cortical surface registration, diffusion MRI, functional imaging, torso image analysis, and tract analysis.
The theoretical results in this monograph indicate that life provides alternative strategies to aging. The groundbreaking findings open a completely new field of research. The author gets away from the human centered vision of life showing that aging in any organism does not necessarily correspond to deterioration and senescence. The central insight of this monograph is: to deeply understand why some species age it is necessary to understand why other species do not.
There have been major developments in the field of statistics over the last quarter century, spurred by the rapid advances in computing and data-measurement technologies. These developments have revolutionized the field and have greatly influenced research directions in theory and methodology. Increased computing power has spawned entirely new areas of research in computationally-intensive methods, allowing us to move away from narrowly applicable parametric techniques based on restrictive assumptions to much more flexible and realistic models and methods. These computational advances have also led to the extensive use of simulation and Monte Carlo techniques in statistical inference. All of...
The language of habit plays a central role in traditional accounts of the virtues, yet it has received only modest attention among contemporary scholars of philosophy, psychology, and religion. This volume explores the role of both “mere habits” and sophisticated habitus in the moral life. Beginning with an essay by Stanley Hauerwas and edited by Gregory R. Peterson, James A. Van Slyke, Michael L. Spezio, and Kevin S. Reimer, the volume explores the history of the virtues and habit in Christian thought, the contributions that psychology and neuroscience make to our understanding of habitus, freedom, and character formation, and the relation of habit and habitus to contemporary philosophical and theological accounts of character formation and the moral life. Contributors are: Joseph Bankard, Dennis Bielfeldt, Craig Boyd, Charlene Burns, Mark Graves, Brian Green, Stanley Hauerwas, Todd Junkins, Adam Martin, Darcia Narvaez, Gregory R. Peterson, Kevin S. Reimer, Lynn C. Reimer, Michael L. Spezio, Kevin Timpe, and George Tsakiridis.