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In the world of drug design and development, Paul Janssen was a giant - responsible for over 80 new medicines in his lifetime. He was the founder of Janssen Pharmaceutica which later merged with Johnson & Johnson. This is the story of his success in building a pharmaceutical 'empire' in China at a time when the country was essentially closed to the west. A fascinating story of remarkable individuals, of business deals and scientific research, of international politics and cultural change, of humanity and ambition.
An intimate profile of the iconic Hollywood Actor, DAVID JANSSEN, by his first wife, ELLIE JANSSEN, as told to Michael Phelps.
This open access book is the first published guide about how to analyse data produced by the EQ-5D, one of the most widely used Patient Reported Outcomes questionnaires world wide. The authors provide practical, clear and comprehensive guidance in five concise chapters. Following an overview of the EQ-5D and its analysis, we describe how the questionnaire data – the EQ-5D profile and EQ VAS – can be analysed in different ways to generate important insights into peoples’ health. We then show how the value sets which accompany the EQ-5D can be applied to summarise patients’ data. The final chapter deals with advanced topics, including the use of Minimally Important Differences, case-mix adjustment, mapping, and more. This book is essential for those new to analyzing EQ-5D data and will be also be valuable for those with more experience. The methods can be applied to any EQ-5D instrument (for example, the three- and five-level and Youth versions) and many of the methods described will be equally relevant to other Patient Reported Outcomes instruments.
A physicist and an inventor, Jules Janssen (1824-1907) devoted his life to astronomical research. He spent many years traveling around the world to observe total Solar eclipses, demonstrating that a new era of science had just come thanks to the use of both spectroscopy and photography, and persuading the French Government of the necessity of founding a new observatory near Paris. He became its director in 1875. There, at Meudon, he began routine photographic recordings of the Sun surface and had a big refractor and a big reflector built. Meanwhile, he also succeeded in building an Observatory at the summit of Mont-Blanc. The story of this untiring and stubborn globe-trotter is enriched by extracts of the unpublished correspondence with his wife. One can thus understand why Henriette often complained of the solitude in which she was left by her peripatetic husband: “There are men who leave their wives for mistresses; you do it for journeys!” ... Basking in the glow of his success, Janssen was able to undertake the construction of the great astrophysical observatory of which he had dreamed. It was at Meudon that he had it built.
Despite their on-again, off-again courtship and his desire not to get married, David allowed Dani Greco to take control of his finances. In his professional life, he becomes Harry O - interjecting a lot of his own real-life eccentricities, endearing him to his fans even more. He went on to assume various roles in 12 Made-for-Television films and 6 Feature films between 1974-1979. We are introduced to Carol Connors, a singer and songwriter David met while collaborating on the song, 'My Sensitive, Passionate Man, ' during a lengthy separation from Dani. He seemed to have found true happiness and had no interest in hiding his relationship with Carol. However, Dani controlled his finances, causing him to feel trapped. Living alone in his Malibu Beach home, David quietly explored the cost of a divorce and learned he would not lose everything. At a time when he likely felt the greatest sense of inner peace, the huge hand of fate brought everything to an end. "DAVID JANSSEN Our Conversations is a heartfelt tribute to a beloved Star, still adored by millions of fans around the world today." Norma Budden, author