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Alzheimer's disease is one of the major scientific, medical and social challenges of our time. This book (the third volume of proceedings of the Colloques Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique) is dedicated to neuronal grafting and Alzheimer's disease. The wealth of basic information presented testifies to the progress that has been achieved in intracerebral grafting and to the utility of intracerebral grafting as a tool for the understanding of brain development, adult neuronal plasticity and age-related pathology. An answer to the question, whether neuronal grafting will be useful as a therapy for Alzheimer's disease, must wait for a better understanding of the disease and the identification of animal models that can be used to test potential therapies. Meanwhile, the tool of intracerebral grafting may, in the future, be used to address the pathophysiology of Alzheimer's disease.
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen. This volume, a collection of articles by the invited speakers and of a few other prominent researchers, is published as a record of those events.
Any mention of the relationship, still poorly understood, between body (or brain) and mind invariably invokes the name of Descartes, who is often thought of as the father of modern philosophy and perhaps of neurophilosophy. Although a native of the heart of France (the region around Tours), Rene Descartes travelled widely, as everyone knows, especially to Holland and Sweden. It should come as no surprise, that the Congress of Neurophilosophy and Alzheimer's Disease was the first in the series of Fondation Ipsen Colloques Medecine et Recherche to be held outside France. The meeting was held in San Diego (California) on January 11, 1991. This venue was chosen for a number of reasons. The Unive...
"Our understanding of how the human brain performs mathematical calculations is far from complete. In The Number Sense, Stanislas Dehaene offers readers an enlightening exploration of the mathematical mind. Using research showing that human infants have a rudimentary number sense, Dehaene suggests that this sense is as basic as our perception of color, and that it is wired into the brain. But how then did we leap from this basic number ability to trigonometry, calculus, and beyond? Dehaene shows that it was the invention of symbolic systems of numerals that started us on the climb to higher mathematics. Tracing the history of numbers, we learn that in early times, people indicated numbers by...
The purpose of this book is to describe the memory system of the brain, taking into account all the levels of neural organization: molecule, cell, small network, and anatomical circuit. This synthetic approach is necessary for determining the real mechanisms among the potential ones, that is the neural bases of learning and memory in intact organisms functioning under normal conditions. For this purpose, data from molecular, cellular and behavioral neurobiology, neuropsychology, animal and human psychology, and neural modellization are comprehensively reviewed by leading specialists and brought together in an original synthesis.
A scientific, uniquely factual account of the role of the brain in freedom and creativity.
"It has come to be widely accepted that "sexuality" as we know it took shape at the end of the nineteenth century, This is when Krafft-Ebing asserted that "sexual feeling is really the root of all ethics, and no doubt of aestheticism and religion," and Havelock Ellis declared sexuality to be the "central problem of life." Yet however self-evident Ellis's claim about sexuality might seem the act of placing something at the center is the consequence of insistent cultural work that engages with competing views about bodies and indeed about the "life" of society. This volume examines how this work was carried out and what resulted from such efforts."--BOOK JACKET.
Henri F. Ellenberger, the Swiss medical historian, is best remembered today as the author of The Discovery of the Unconscious (1970), a brilliant, encyclopedic study of psychiatric theory and therapy from primitive times to the mid-twentieth century. However, in addition to this well-known work, Ellenberger has written over thirty essays in the history of the mental sciences. This collection unites fourteen of Ellenberger's most interesting and methodologically innovative historical essays, many of which draw on new and rich bodies of primary materials. Several of the articles appear here in English translation for the first time. The essays deal with subjects such as the intellectual origin...
This volume contains the proceedings of the meeting Genetics and Alzheimer's Disease held in Paris, on March 25,1988, by the Fondation Ipsen pour la Recherche Therapeuti que. This meeting was the second of the series of Colloques Medecine et Recherche devoted to Alzheimer's disease. The first one was held in Angers (France) on September 14, 1987; the proceedings of this meeting have already been published and are entitled Immunology and Alzheimer's Disease (1988, edited by A Pouplard-Barthelaix, J Emile, and Y Christen). The third Colloque Medecine et Recherche, organized in Montpellier on Sep tember 19, 1988, dealt with neuronal grafting; the proceedings of this last meeting will be publish...