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This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
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Volume of the United States Reports containing the final decisions and opinions of the Supreme Court justices regarding cases between October 6, 2005 and March 6, 2009. Also includes notes regarding the members of the Supreme Court, orders, and other relevant materials.
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Winner of the Aventis Science Book Prize. 'A scientific detective story, a brilliant cross between Edgar Allan Poe and Gray's anatomy' J G Ballard, New Stateman Books of the Year 'Fascinating' New Scientist 'Wonderful' Nature - What is the connection between Paul McCartney, Leonardo Da Vinci and Babe Ruth? - Why are parrots and peacocks left-footed? - Do left-handers behave differently from right-handers? - Why are most people right-handed? - Why are all muppets left-handed? - Why is the heart on the left-hand side of the body? - Why is each side of the human brain so different? RIGHT HAND, LEFT HAND uses sources as diverse as the paintings of Rembrandt and the sculpture of Michelangelo, the behaviour of Canadian cichlid fish and the story of early cartography. Modern cognitive science, the history of the Wimbledon tennis championship and the biographies of great musicians are also used to explain the vast repertoire of 'left-right' symbolism that permeates our everyday lives.