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Function and Regulation of Chemoreceptors
To perceive environmental chemical compounds and to convert these external signals into an intracellular message might be the oldest way for a living being to get information from the outside world. Chemoreceptors are proteins or protein complexes that detect molecules from the outside world either at distance (olfaction) or at close range (gustation). Chemoreceptors can operate as ionotropic or as metabotropic receptors. Ionotropic receptors form ion channels that are activated via ligand binding. Activation of a metabotropic receptor initiates an intracellular signaling cascade that could include a change of enzymatic activity, production of second messenger or activation of ion channels. The receptor performance has to be fine-tuned according to the actual physiological requirements and the presentation of the chemical signal. This Research Topic collects reports and reviews on structure and function of chemoreceptors in the animal kingdom, and how these receptors are regulated.
G Protein-Coupled Receptors
G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation. - Covers the increasingly appreciated cell biology field of G-protein-coupled receptors - Includes both established and new technologies - Contributed by experts in the field - Covers topics such as signaling, trafficking, and regulation
Chemosensory Transduction
Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutr...
Kindling 6
Proceedings of the Sixth International Conference on Kindling, featuring valuable summaries of the participants’ current cutting-edge research on the kindling of seizures and related phenomena in epilepsy.
Congressional Record
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The Illustrated World of Mortal Engines
It was a dark, blustery afternoon in spring, and the city of London was chasing a small mining town across the dried-out bed of the old North Sea. So begins Philip Reeve's Mortal Engines, the first book in his epic post-apocalyptic series of giant motorized cities on wheels. But how did the world end up like this? What led to the downfall of our civilization, and to the rise of the Traction Cities that roam the Great Hunting Ground to attack and devour each other? Now, for the first time, discover the untold future history of Traction. This lavishly illustrated book contains incredible tales of fearsome Zagwan warriors riding war-zebras into battle, daring air-traders flying the Bird-Roads in search of adventure, and the mysterious plague-ridden wasteland of the Dead Continent that was formerly known as 'North America'. This definitive companion guide includes detailed maps, fascinating character profiles, and stunning colour illustrations from incredible artists, including Ian McQue, David Wyatt, Aedel Fakhrie, Maxime Plasse, Rob Turpin, Philip Varbano and Amir Zand. MORTAL ENGINES is soon to be a major motion picture.
