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Combinational Immunotherapy of Cancer: Novel Targets, Mechanisms, and Strategies
Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manip...
Evidence-based Advance and Management of Adverse Events of Immunotherapy for Cancer
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Artificial Intelligence and Security
The 3-volume set CCIS 1252 until CCIS 1254 constitutes the refereed proceedings of the 6th International Conference on Artificial Intelligence and Security, ICAIS 2020, which was held in Hohhot, China, in July 2020. The conference was formerly called “International Conference on Cloud Computing and Security” with the acronym ICCCS. The total of 178 full papers and 8 short papers presented in this 3-volume proceedings was carefully reviewed and selected from 1064 submissions. The papers were organized in topical sections as follows: Part I: artificial intelligence; Part II: artificial intelligence; Internet of things; information security; Part III: information security; big data and cloud computing; information processing.
