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Progress and Challenges in Transfusion Medicine, Hemostasis, and Hemotherapy
Modern transfusion medicine is sophisticated hemotherapy. Cellular and humoral blood components can be relevant in virtually every disease, either as a primary determinant in pathophysiology or as a victim of collateral damage, e.g. during treatment with cytostatic drugs, or as crucial substrates in replacement and hemostasis-navigated hemotherapy. With its interdisciplinary approach modern hemotherapy is a paragon of translational research bridging the bench-to-bedside gap in biomedicine. The state-of-the-art contributions collected here aim to stimulate lively discussions ' not only among blood center professionals but also with blood and vascular biologists, hematologists, immunologists, anesthesiologists, intensive care specialists, surgeons, cardiologists, nephrologists, rheumatologists, and pulmonary and infectious disease specialists.
Clinical Cardiogenetics
Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis an...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Progress in Monogenic Hair Disorders
In the present monograph, leading figures in the field of genetic hair research summarise major recent advances. View as a whole, these reviews of each of the major areas of hair genodermatology not only illustrate the importance of recent findings to our understanding of skin biology and the management of hair disorders, but also underscore the relevance of hair genetic research to non-cutaneous pathologies. The wealth of recent discoveries combined with the application of emergent technologies to the study of hair biology and diseases have placed this discipline at the forefront of biological research, generating unprecedented challenges for investigative dermatology that are transpiring throughout this new and pioneering book.
Case Reports in Neurogenetics, volume III - 2023
This Research Topic aims to collect all the Case Reports submitted to the Neurogenetics. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it. Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course.
Focus on Medical Genetics and Down's Syndrome Research
Medical Genetics is the application of genetics to medicine. Medical genetics is broad and varied and encompasses many different individual fields, including clinical genetics, biochemical genetics, cytogenetics, molecular genetics, the genetics of common diseases (such as neural tube defects), and genetic counselling. Each of the individual fields within medical genetics is a hybrid. Clinical genetics is a hybrid of clinical medicine with genetics. Biochemical genetics is a hybrid of biochemistry, mainly the biochemistry of amino acids and proteins, with genetics. Molecular genetics is a hybrid of the biochemistry of DNA and RNA with genetics. Cytogenetics is a hybrid of cytology and genetics; it involves the study of chromosomes under the microscope. And genetic counselling is a hybrid of genetics with non-directional counselling. This book presents leading-edge research on medical genetics as well as on Down's syndrome.
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Characterization and Clinical Management of Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis and uninterrupted and tailored follow-up under constant optimal medical and non-pharmacological evidence-based treatments. Nevertheless, DCM is still one of the most common causes of heart transplantation in the western world. Clinical management requires an integrated and systematic use of diagnostic tools and a deeper investigation of the basic mechanisms underlying the disease. However, severa...
Oncology of CNS Tumors
This book is an easy-to-use reference that provides ready guidance on the diagnosis and treatment of the full range of tumors of the central nervous system in adults and children. The new edition has been completely revised to reflect the continually evolving landscape of neuro-oncology and provide readers with a thorough update that will inform their clinical practice. Since the previous edition, molecular neuropathology has progressed considerably, leading to a new understanding of specific clinical entities with corresponding changes in treatment concepts. Moreover, tumor biology has become better integrated with clinical neuro-oncology in truly translational efforts. These advances receive detailed attention. In addition, the structure of the book has been adapted to align with the revised 2016 version of the WHO Brain Tumor Classification. Once again, the contributors have been carefully selected as leading experts in the field. Oncology of CNS Tumors is already established as a widely used reference, and this new edition will provide optimal value for highly specialized comprehensive neuro-oncology centers as well as practicing clinicians and researchers.
