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LESLIE L. IVERSEN The present series of volumes is well timed, as the impact of molecular genetics on pharmacology has been profound, and a comprehensive review of the rapid advances of the past decade is much needed. Since the pioneering work of Dale, Ariens, and others in the early years of this century, much of pharmacology has been founded on the concept of receptors. To begin with, the receptor was conceived of as a "black box," which recognized and transduced the biological effects of neurotransmit ters, hormones, or other biological messengers-and which could also represent a target for man-made drugs. It is only in the last two decades that "molecular pharmacology" has blossomed, fir...
This work presents, in an easy-to-use tabular format, a complete list of the 25,000 persons who bought land in southwestern Ohio and eastern Indiana through the Cincinnati Land Office between the years 1800 and 1840. Data furnished with each entry includes the name of the purchaser, date of purchase, place of residence at the time of purchase, and the range, township, and section of the purchased land, thus enabling the researcher to ascertain the exact location of an ancestor's land. Previously, in locating a settler in southwestern Ohio, the researcher was obliged to spend hours if not days searching through numerous volumes of unindexed land records, but with this volume the task is reduced to seconds.
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This long out-of-print genealogical reference has become much sought after by residents of Washington County, Virginia, and the numerous scattered descendants of that county's forefathers. The work identifies 333 Washington County cemeteries and cites the inscriptions of each tombstone. Seven detailed maps aid in locating the burial sites. This edition also includes a newly compiled comprehensive index of more than 2,400 surnames, many of which include multiple entries.