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The stuff of nightmares in both their looks and the wounds inflicted on their victims, sea lampreys (Petromyzon marinus) are perhaps the deadliest invasive species to ever enter the Great Lakes. At the invasion’s apex in the mid-20th century, harvests of lake trout (Salvelinus namaycush), the lampreys’ preferred host fish in the Great Lakes, plummeted from peak annual catches of 15 million pounds to just a few hundred thousand pounds per year—a drop of 98% in only a few decades. Threatening the complete collapse of the fishery, the sea lamprey invasion triggered an environmental awakening in the region and prompted an international treaty that secured unprecedented cooperation across p...