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Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secreti...
This book gathers peer-reviewed proceedings of the 3rd International Conference on Innovative Computing (IC 2020). This book aims to provide an open forum for discussing recent advances and emerging trends in information technology, science, and engineering. Themes within the scope of the conference include Communication Networks, Business Intelligence and Knowledge Management, Web Intelligence, and any related fields that depend on the development of information technology. The respective contributions presented here cover a wide range of topics, from databases and data mining, networking and communications, the web and Internet of Things, to embedded systems, soft computing, social network analysis, security and privacy, optical communication, and ubiquitous/pervasive computing. Readers such as students, researchers, and industry professionals in the fields of cloud computing, Internet of Things, machine learning, information security, multimedia systems, and information technology benefit from this comprehensive overview of the latest advances in information technology. The book can also benefit young investigators looking to start a new research program.
In recent years wrist problems have increasingly attracted the attention of orthopaedic and hand surgeons. Numerous advances have been achieved in functional anatomy, biomechanics, diagnosis, and treatment. There are, however, many controversial aspects to these problems. Many clinical and associated investigators from around the world have attempted to increase our knowledge of the wrist with enthusiastic and devoted studies. An international symposium was held at the Nagoya Castle Hotel, Nagoya, Japan from March 6th through March 8th, 1991 to further understanding and promote discussion of wrist problems among a representive international group. Approximately 300 participants from 16 diffe...
This book comprises a selection of papers on new methods for analysis and design of hybrid intelligent systems using soft computing techniques from the IFSA 2007 World Congress, held in Cancun, Mexico, June 2007.
This volume constitutes the refereed proceedings of the International Conferences, FGCN and DCA 2012, held as part of the Future Generation Information Technology Conference, FGIT 2012, Kangwondo, Korea, in December 2012. The papers presented were carefully reviewed and selected from numerous submissions and focus on the various aspects of future generation communication and networking, and digital contents and applications.
Issues for 1973- cover the entire IEEE technical literature.
Nanotechnology has the potential to drastically transform the agri-food sector with its significant applications to improve agricultural productivity and the efficiency of agrochemicals. The food sector has benefitted from the inclusion of nanoparticles in food matrixes and the nanoencapsulation of nutraceuticals. Smart packaging materials designed with the help of nanotechnology have been used for increasing the shelf life of stored food products. Nanomaterials have been extensively used for the delivery of important agrochemicals to enhance their bioefficacy, prevent their degradation, and control their release. Various nanomaterials have been explored for remediation of arising environmen...
This book constitutes the refereed proceedings of the Second International Conference on Knowledge Science, Engineering and Management, KSEM 2007, held in Melbourne, Australia, in November 2007. The 42 revised full papers and 28 revised short papers presented together with five invited talks were carefully reviewed and selected. The papers provide new ideas and report research results in the broad areas of knowledge science, knowledge engineering, and knowledge management.