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The Rise of the Scientist-Bureaucrat
"Perez Velazquez has written a little gem that I advise reading to anyone persuing a scientific career, as well as for the general public interested in the sociological aspects of science. It alerts the reader about the rise of a new type of scientist, buried in bureaucracy and financial issues. In contrast to past generations, this "new scientist" is sadly left with minimal time to dedicate to creative work. It studies the consequences of this state of affairs, the problems associated with peer reviewing, the dilemma of funding innovative research, the nature of corporate academic culture and the trivialization of scientific achievement by grant agencies and universities. It also provides p...
Being and becoming
Many people spend considerable time seeking a sense of purpose in life and, concomitant with that, a sense of personal identity. This book demystifies this search, revealing why this search is a fallacy. The purpose is to inform readers about results in neuroscience and biophysics that may guide us to some liberation needed in the current age of great complexity in life with a diverse burden of chores; a deliverance from some afflictions that prevent individuals from achieving the true purpose of our lives. Among these afflictions we find two primordial concerns: the belief and subsequent attachment to a self, and the conviction that life must have a deep purpose in which we are major player...
The Brain-behavior Continuum
This book is a comprehensive overview of the main current concepts in brain cognitive activities at the global, collective (or network) level, with a focus on transitions between normal neurophysiology and brain pathological states. It provides a unique approach of linking molecular and cellular aspects of normal and pathological brain functioning with their corresponding network, collective and dynamical manifestations that are subsequently extended to behavioural manifestations of healthy and diseased brains. This book introduces a high-level perspective, searching for simplification amongst the structural and functional complexity of nervous systems by consideration of the distributed int...
Coordinated Activity in the Brain
Increasing interest in the study of coordinated activity of brain cell ensembles reflects the current conceptualization of brain information processing and cognition. It is thought that cognitive processes involve not only serial stages of sensory signal processing, but also massive parallel information processing circuitries, and therefore it is the coordinated activity of neuronal networks of brains that give rise to cognition and consciousness in general. While the concepts and techniques to measure synchronization are relatively well characterized and developed in the mathematics and physics community, the measurement of coordinated activity derived from brain signals is not a trivial ta...
Gap Junctions in the Brain
In addition to chemical links across synapses, neurons can also form direct connections via electrical gap junctions. These channels play a key role in brain development and intercellular communication. Dere (pathophysiology of cerebral aging, U. Pierre et Marie Curie, Paris; AP-HP Hôpital Charles Foix, Centre de Recherche et Développement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. The text includes color and b&w illustrations including schematic representations and models. Academic Press is an imprint of Elsevier. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com).
Gap Junctions in the Nervous System
This book deals with the types of gap junction proteins (connexins) and their distribution within the nervous system, the physiological properties of channels formed of each connexin, and the role of gap junction channels in functions of normal and pathological brain and peripheral nerve. Although glial tissue is emphasized, additional groups of chapters deal with neurons in the central nervous system and with the retina.
Neurobiology of Disease
Preceded by Neurobiology of disease / edited by Sid Gilman. 2007.
Connexin Methods and Protocols
Direct cell–cell communication is a common property of multicellular organisms that is achieved through membrane channels which are organized in gap junctions. The protein subunits of these intercellular channels, the connexins, form a multigene family that has been investigated in great detail in recent years. It has now become clear that, in different tissues, connexins speak several languages that control specific cellular functions. This progress has been made possible by the availability of new molecular tools and the improvement of basic techniques for the study of membrane channels, as well as by the use of genetic approaches to study protein function in vivo. More important, connex...
Jhana Consciousness
An interdisciplinary deep dive into Buddhist jhāna meditation and how it can transform our understanding of self and consciousness States of profound meditative concentration, the jhānas are central to the earliest Buddhist teachings. For centuries in Southeast Asia, oral yogāvacara (yoga practitioner) lineages kept traditional jhāna practices alive, but in the nineteenth and twentieth centuries, reforms in Theravāda Buddhism downplayed the importance of jhāna in favor of vipassanā (insight) meditation. Some began to consider the jhānas to be strictly the domain of monastics, unattainable in the context of modern lay life. In recent years, however, there has been a resurgence of inte...
The Man Beside
Steve Campion never planned on being a drunk, and he certainly never planned on writing about it. But things just have a way of happening. In The Man Beside, he offers a very personal look at addiction and recovery, offering hope tempered with the reality of how difficult recovery can be. Campion shares a series of short narratives, observations, and thoughts, including snapshots from his childhood, musings about his past, and discussion about his journey to becoming clean and sober. Through these memories, he tells how it was the combination of moments that led him into and out of using. Campion admits his substance abuse, addiction, and recovery have helped to define who he is and where he's going. The Man Beside offers unique insight into what's really going on in an addicted mind, helping others understand they are not alone on their road to recovery.
