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Innate Lymphoid Cell Development, Migration, and Function
Cell lineages derived from common lymphoid progenitors (CLPs) play a critical role in antigen recognition, acute and long term protection against pathogens, and maintenance of immune homeostasis. CLPs give rise to adaptive immune cells that bear unique antigen receptors and to innate immune cells that perform non-redundant roles, particularly during early effector responses, by facilitating local immunity and shaping the ensuing adaptive response. Recent discoveries indicate that innate lymphoid cells (ILCs) exert essential modulatory effects in normal and pathological responses. Because adaptive and innate lymphoid cells share transcription factors, cytokines, and molecular surface markers,...
Rheumatology
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from ...
Systemic Lupus Erythematosus
Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date,...
Firestein & Kelley's Textbook of Rheumatology - E-Book
With its comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, Firestein & Kelley's Textbook of Rheumatology remains your reference of choice in this evolving field. The fully revised 12th Edition retains the user-friendly, full color format, providing in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. New editors, new chapters, and new illustrations keep you fully up to date on recent advances in genetics and the microbiome, current therapies, and other rapid changes in the field. - Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedur...
The Jurist
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Estudios sociales
El Comité Organizador del 56º Congreso Internacional de Americanistas (ICA) publica las actas del encuentro celebrado en la Universidad de Salamanca el 15 al 20 de julio de 2018. Bajo el lema «Universalidad y particularismo en las Américas», reflexionó sobre la dialéctica entre la universalidad y los particularismos en la producción de conocimiento, un diálogo en el que la necesidad de conocer los particularismos de los fenómenos sociales, políticos, artísticos y culturales obliga a formular nuevas hipótesis que enriquecen y replantean las grandes teorías generales de las ciencias y las humanidades. El carácter interdisciplinario e inclusivo que ha caracterizado al ICA desde s...
