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Principles of Molecular Medicine
  • Language: en
  • Pages: 1299

Principles of Molecular Medicine

The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been med...

Principles of Molecular Medicine
  • Language: en
  • Pages: 1070

Principles of Molecular Medicine

Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.

The Molecular and Cellular Biology of Wound Repair
  • Language: en
  • Pages: 624

The Molecular and Cellular Biology of Wound Repair

'Provides comprehensive detail on the various aspects of particular molecules involved in the phases of injury and repair and the cellular movements and processes....This is an excellent reference book for libraries serving biology and health science clientele and for workers in this field of research.' -American Scientist, from a review of the First Edition All chapters of this second edition have been completely revised and expanded-especially the chapters on growth factors and extracellular matrix molecules. New chapters discuss provisional matrix proteins, extracellular matrix receptors, and scarring versus nonscarring wound healing.

Biology of the Integument
  • Language: en
  • Pages: 870

Biology of the Integument

The integument plays an important role in the survival of meta zoans by separating and protecting them from a hostile environ ment. Its function ranges from protection against injury and in fection, participation in the regulation of body temperature and water balance, to respiratory activity, monitoring of the environ ment and production of signals related to behaviour. All these result from specific structural, biochemical and physiological properties of intra-and extracellular components of the integu ment. Thus its characterization can be best accomplished by a multidisciplinary approach with authors specialized in different fields of science. This multi-author book, in two volumes, prov...

Skin Moisturization
  • Language: en
  • Pages: 518

Skin Moisturization

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

Focusing on the scientific basis of skin moisturization, this expanded Second Edition of Skin Moisturization explores a wide range of topics, from the biological aspects of the skin to the formulation of the active ingredients in skin moisturizers. Ideal for dermatologists, cosmetic scientists, and clinical scientists interested in the treatment of

Human Papillomaviruses and Polyomaviruses in Skin Cancer
  • Language: en
  • Pages: 160

Human Papillomaviruses and Polyomaviruses in Skin Cancer

Nonmelanoma skin cancer (NMSC), more recently defined as keratinocyte carcinoma (KC), is the most frequent malignant tumor among Caucasians. This book deals with widely distributed cutaneous papillomaviruses and polyomaviruses, which are able to establish life-long persistent infections. They are frequently clinically inapparent in the general population, but can cause skin cancer in immunocompromised hosts or in the aging skin undergoing immunosenescence, thereby leading to major medical problems. The incidence of cutaneous squamous cell carcinoma (cSCC) in immunosuppressed organ transplant recipients is 60-250 times higher than that observed in the general population, which is highly sugge...

The ABC Transporters of Human Physiology and Disease
  • Language: en
  • Pages: 478

The ABC Transporters of Human Physiology and Disease

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins that are likely to be represented in all the cells of all species of archaea, eubacteria and eukaryota. The vast majority of these proteins control the transport of molecules (from small hydrophilic ions to lipids and proteins) across cellular membranes. The human genome encodes 48 ABC transporters and most have been shown to underlie one or more human diseases. This book that brings together state-of-the-art knowledge on proteins in one volume will provide students, professors and medical professionals with a background to the human ABC transporters that are known to be relevant to diseases. Each of the 14 chapters is written by a leading researcher in the field and includes contributions from Joe Bryan and Lydia Aguilar-Bryan, Kazu Ueda, Jack Riordan and Robert Tamp. The genetics, structure and function of the proteins, and the future direction of research including the implications for human health are discussed in depth.

This Mortal Coil
  • Language: en
  • Pages: 302

This Mortal Coil

"Hamlet's "mortal coil" - which eventually and inevitably we "shuffle off" when we enter the sleep of death, as he puts it - has never been static. Indeed how the human body and its component parts have been understood, individually and collectively, has shifted across time, shaped by culture, religion, and technology. In this probing and provocative new book, Fay Bound Alberti uses the global histories of medicine, pathology, and emotions to explore these changing notions. Each chapter uses a different focus - bones, skin, sexual organs, spine, tongue, heart - revealing how each body part connects to a peculiarly Western notion of expertise, one which appropriates one element from the other...