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This book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.
International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - Microfibrils from the Arterial Subendothelium - Cultivation and Transplantation of Epidermal Keratinocytes - Retinoids and Mammalian Development - Gene Expression in the Epididymis - Reactive Oxygen Role in Signaling and Regulation - High-Density Lipoproteins
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Essential to anyone working in the field, this reference focuses on latest advancements in tissue construction, repair and regeneration focusing on developments in gene and drug therapy, the evolution of tissue-engineered products, and new technologies for the design of functional tissues and organ systems.
Substantially revised to reflect the most recent surgical techniques and practices, this reference describes the most effective strategies to prevent, identify, and manage complications in vascular surgery-guiding surgeons through patient selection; instances of entrapment, malpositioning, and rupture; emerging endovascular treatments; and specific
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