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The functional and organic alterations of the colon constitute one of the leading reasons why patients consult gastroenterologists. The irritable colon is one of the most com mon causes of discomfort in human beings. The organic pathology of the large bowel (malignancy and chronic inflammatory disease) contributes, particularly among Occi dental peoples, to discouragingly high levels of morbidity and mortality. One realizes the importance of having a thorough physiologic knowledge of the colon in order to scientifically plan the functional treatment of organic colonic dis eases. If we consider the large amount of material published on the physiology of the esophagus, stomach, small bowel, pa...
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The Harry Potter series may be named after the Boy Who Lived, but if you want to know the story, keep your eyes fixed on Severus Snape. This hook-nosed, greasy-haired, grumpy character is one of J.K. Rowling's enduring gifts to English literature. He's the archetypal ill-tempered teacher: acerbic, yet horribly, deliciously funny. When he's in a scene, you can't take your eyes off him. Snape is always the story. - From the Introduction In this examination of J.K. Rowling's most enigmatic character, Lorrie Kim shows us how to sort through the illusions and lies to the man who dared to spy on Voldemort. In his final moments, he asks Harry, and the reader, to "Look at me." This book does just that.
Antibiotic resistance is a global health concern. Strains of pathogenic microorganisms that have developed resistance to multiple antibiotics, such as MRSA, are extremely difficult to treat, and alternative methods for tackling pathogenic microorganisms are in demand. One potential target for new therapeutics is inhibition of quorum sensing: how microorganisms communicate and form biofilms in a density-dependent manner. Inhibiting this system via ‘quorum quenching’ (QQ) is a promising route to new pharmaceuticals and for controlling biofilm formation and growth. Quorum sensing also provides interesting possibilities in synthetic biology for producing novel products, biosensors, bioactive...
Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. PRAISE FOR THE SERIES "No laboratory scientist, field worker or technical administrator can afford to pass it up." ASM NEWS "The topics are well supported by an extensive bibliography and provide a rich source of current information." BIOPHARM
Innervation of the Gut provides a stimulating discussion of gut innervations based on exciting developments generated by advanced neuroanatomical and electrophysiological approaches. All components of the nervous system are covered, including central, spinal, autonomic, and enteric systems. This information is relative to secretory, motor, and immune regulatory functions of the gut, as well as visceral sensation. Brain transmitters involved in mediating stress-induced alterations of gastrointestinal motor function and the central regulation of vagal outflow to the gut are discussed in detail. The book will stimulate basic scientists and gastroenterologists to expand research efforts that may enable them to unravel the mechanisms of brain-gut interactions under physiological and pathological conditions. Students, psychologists, and psychiatrists will find Innervation of the Gut an essential reference for their studies.
Sphincters: Normal Function-Changes in Diseases is the first book devoted to sphincter function in health and disease. It provides basic information about the function of sphincters and their physiological controls, as well as a comprehensive examination of the various sphincters in the body. The book also presents the current understanding of disordered control of sphincter function in disease. Sphincters: Normal Function-Changes in Diseases is an important acquisition for scientists, physicians, and medical students interested in sphincter function and how to treat their disorders.
Physicians treating patients with Inflammatory Bowel Disease (IBD) often face challenges due to the disease itself, associated conditions, and systemic effects. Recently, new medications have been introduced that allow for more aggressive and effective treatment of IBD. With these medications come the risks of adverse side effects, and physicians must vigilantly monitor for any complications. Drs. Miguel D. Regueiro and Jason Swoger have created a unique, user-friendly book that describes how to prevent, recognize, and manage complications encountered in the care of patients with IBD. Clinical Challenges and Complications of IBD aims to provide practical and clinically oriented information t...
This volume places more emphasis on endogenous mediators of gut motility than on drugs used to treat patients with deranged motility. In this respect it resembles most other books on gastroenterology, for while only a relatively small number of drugs are really useful for a rational therapy, a tremendous amount of data is available on neural and hormonal factors regulating the motility of the alimentary canal. Moreover, it must be considered that some of the drugs which can routinely be employed to modify deranged motility of the digestive system are represented by pure or slightly modified endogenous compounds (e. g. , cholecystokinin, its C terminal octapeptide and caerulein), and it is ea...