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Neurobiology of Grooming Behavior
Grooming is among the most evolutionary ancient and highly represented behaviours in many animal species. It represents a significant proportion of an animal's total activity and between 30-50% of their waking hours. Recent research has demonstrated that grooming is regulated by specific brain circuits and is sensitive to stress, as well as to pharmacologic compounds and genetic manipulation, making it ideal for modelling affective disorders that arise as a function of stressful environments, such as stress and post-traumatic stress disorder. Over a series of 12 chapters that introduce and explicate the field of grooming research and its significance for the human and animal brain, this book covers the breadth of grooming animal models while simultaneously providing sufficient depth in introducing the concepts and translational approaches to grooming research. Written primarily for graduates and researchers within the neuroscientific community.
Behavioral Models in Stress Research
Stress is an adaptive response that has developed throughout evolution, and is associated with multiple changes in the biochemistry, histology and physiology of an organism. As stress may induce or contribute to multiple neuropsychiatric disorders, the rigorous investigation of the neural substrates of stress has become a critical endeavour of contemporary biomedical science. This book explores the physiological responses that researchers have attempted to assess in stress-evoked behavioural changes, using both human and animal "experimental" models in clinical and non-clinical research. Though all aspects of the field have their challenges, animal experimental research of stress is a particularly difficult but meaningful task. This book provides succinct and relevant summaries of progress in the area of assessing stress response and the conditions contributing to it.
Dirty Drugs
Psychische Erkrankungen gehoren epidemiologisch weltweit zu den verbreitetsten Krankheitsrisiken. Psychopharmaka pragen unsere Gesellschaft starker, als uns dies bewusst ist. Gleichwohl ist der rechtliche Rahmen der psychopharmakologischen Forschung und Therapie fragmentiert sowie teils von vorrationalen Pfadabhangigkeiten gepragt. Die vorliegende Untersuchung geht von der Geschichte der wissenschaftlichen Psychopharmakologie sowie den neurochemischen Wirkungsmechanismen typischer Psychopharmaka aus. Klaus Ferdinand Garditz analysiert die wildwuchsigen Regelungsstrukturen und die damit verbundenen Wechselwirkungen zwischen Pharmakologie, Gesellschaft und Recht als institutionelle Herrschafts...
Soziologie der Angst
Max Dehne entwickelt in seiner Arbeit Grundlagen für eine systematische soziologische Untersuchung von Angst. Sein interdisziplinär anschlussfähiges Konzept erlaubt es, die sozialstrukturellen und kulturellen Bedingungen von Angst sowie angstbezogener Mechanismen systematisch zu bestimmen. Mithilfe eines Modells, das sich an Theorien dynamischer Systeme orientiert, werden diese Aspekte als Bestandteile eines von komplexen Wechselwirkungen geprägten, gleichermaßen psychischen wie sozialen Angstprozesses fassbar. Im empirischen Teil untersucht der Autor die historische Entwicklung und soziale Verteilung von Angst. Dabei zeigen sich weder Hinweise auf eine gegenwärtige Angstgesellschaft noch auf eine besonders ausgeprägte „German Angst“. Zahlreiche weitere Detailergebnisse verweisen darüber hinaus auf ein erhebliches Potenzial für die zukünftige empirische Sozialforschung zu Angst.
Bibliographic Index
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Animal Genetics
The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding. Many aspects of human and animal behaviors have a strong genetic contribution. Individual variation in different behaviors is also found across animal populations. Animal models are increasingly being used to look for genes underlying these naturally occurring variations in behaviors and the most common species of animals used experimentally are mice and rats. This new and important book gathers the latest research from around the globe in this dynamic field of study with a focus on such topics as: phylogeography of finches and sparrows, pig genomics and transgenesis in biomedical research, epigenetic regulation in bovine cells, understanding the stress response through mouse genetics and others.
Just Before Sleep
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Chemical Engineering in the Pharmaceutical Industry
A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredie...
