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This volume explores the conceptual framework and the practical issues related to genomic prediction of complex traits in human medicine and in animal and plant breeding. The book is organized into five parts. Part One reminds molecular genetics approaches intending to predict phenotypic variations. Part Two presents the principles of genomic prediction of complex traits, and reviews factors that affect its reliability. Part Three describes genomic prediction methods, including machine-learning approaches, accounting for different degree of biological complexity, and reviews the associated computer-packages. Part Four reports on emerging trends such as phenomic prediction and incorporation i...
This volume explores the conceptual framework and the practical issues related to genomic prediction of complex traits in human medicine and in animal and plant breeding. The book is organized into five parts. Part One reminds molecular genetics approaches intending to predict phenotypic variations. Part Two presents the principles of genomic prediction of complex traits, and reviews factors that affect its reliability. Part Three describes genomic prediction methods, including machine-learning approaches, accounting for different degree of biological complexity, and reviews the associated computer-packages. Part Four reports on emerging trends such as phenomic prediction and incorporation i...
This sweeping generational novel, which spans the 20th century, begins with an old man considering a photograph of his long-dead siblings and mother. His bitterness about his family, with its absent father and far older brothers and sisters, is painful to him still. Yet this familial bitterness pales when compared with his profound irritation at the recent disappearance of the highly skilled barmistress Hayet from his local bar. She was, after all, a woman who knew how to make a fine home away from home for her patrons--even for lonely ones like Marcel. A succession of would-be barmen and hostesses descends on the Corsican bar in the hopes of taking Hayet's place, with disastrous and often h...
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