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This book presents results of lifespan prolongation studies obtained from experimental animal models and clinical and epidemiological human investigations. Modern theories, experimental models, and mathematical models of aging are described, as well as factors identified in lifespan prolongation, such as reduced body temperature, calorie- and protein-restricted diets, antioxidants, enterosorption, motor activity, modulators of genome expression, ionizing radiation, vitamins, microelements, and revitalizers. Gerontologists, physiologists, biochemists, and physicians active in the field of aging will find this book to be an interesting addition to their reference library.
First multi-year cumulation covers six years: 1965-70.
Encyclopedia of Biomedical Gerontology, Three Volume Set presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention. Provides a ‘one-stop’ resource to information written by world-leading scholars in the field of biomedical gerontology Fills a critical gap of information in a field that has seen significant progress in the last 10 years
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It can be argued that ATP is the most important molecule in cells. Not only is ATP the key energy source for cells, but it is also the source of phosphate groups that are transferred to a variety of substrate proteins via the action of elaborate families of protein kinases. An equally elaborate array of protein phosphatases can remove phosphate groups from proteins. It is now well established that protein phosphorylation is a widely used mechanism for cells to selectively modulate the function of a variety of proteins including enzymes, ion channels and pumps and structural proteins. In this volume of ACAG leading experts describe the evidence that protein phosphorylation is altered in aging...
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