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The Cover Image for This Research Topic is Used With Permission of the Authors and Publishers of the Following Article: Winkler J, Seybert A, König L, Pruggnaller S, Haselmann U, Sourjik V, Weiss M, Frangakis AS, Mogk A, Bukau B.EMBO J. 2010 Mar 3;29(5):910-23. doi: 10.1038/emboj.2009.412. Epub 2010 Jan 21
Game culture and material culture have always been closely linked. Analog forms of rule-based play (ludus) would hardly be conceivable without dice, cards, and game boards. In the act of free play (paidia), children as well as adults transform simple objects into multifaceted toys in an almost magical way. Even digital play is suffused with material culture: Games are not only mediated by technical interfaces, which we access via hardware and tangible peripherals. They are also subject to material hybridization, paratextual framing, and processes of de-, and re-materialization.
Derrick's desire to save one human girl will ignite a war... For four thousand years, creatus have concealed themselves from the humans who hunted them almost to extinction. Unwittingly, one creatus will endanger them all... As with most of his family, Derrick Ashton knows his future and what position he's destined to fill within his unique society. Everything changes, however, when he breaks one of his family's strictest laws and falls in love -- with a human. In his quest to protect the woman he can never have, a twist of fate propels him into a new role that will cause dissension among his family and endanger the anonymity that they've spent thousands of years protecting. Now, he will ...
Being able to collect valid data is crucial for empirical science disciplines such as linguistics, developmental psycholinguistics, clinical psycholinguistics and speech and hearing sciences. In recent years there has been an increasing use of digital devices for remote language assessments, such as online elicitation of language samples, apps for eliciting expressive and productive lexical abilities, and online questionnaires. With the ongoing COVID-19 pandemic still affecting many lives globally, there have been numerous disruptions of face-to-face, in-person language assessments, leading many researchers to conduct their language assessments online. Despite the necessity of remote languag...
A comprehensive reference on the state of the science for both experienced researchers and for those who are interested in discovering its many promising applications. • Examines c-di-GMP signaling from a variety of angles, beginning with an introductory chapter that compares c-di-GMP to the better-known second messenger cAMP. • Recounts the discovery of c-di-GMP, explains the important role of bioinformatics in the development and continued evolution of the field, and describes the fundamental structure, function, regulation, and integration of c-di-GMP pathways. • Explores the role of c-di-GMP in such diverse processes as flagellar biogenesis and motility, extracellular polysaccharide biosynthesis, biofilm development, virulence, and innate host immunity.
They were ordinary people caught in an extraordinary time. The ships engines made a deep rumbling sound like thunder and there was a steady tremor under their feet. Then the ships whistle blew loud and long. The engines began a steady drumbeat, which was even louder than the rumbling sound. Charlie and Ida looked at each other. Ida could see fear in Charlies eyes. The next moment, Charlie hugged her, and she returned his embrace. I guess were off to America! Charlie shouted. Theres no turning back now! So begins the story of six siblings, who in the 1800s, filled with courage and hope, left their home in Sweden to discover a new life in America. Driven to escape hunger and poverty, they were...
For a quarter century, I’ve pursued genealogical minutiae—the particulars of family compositions in the townlands of Eastern County Mayo and nineteenth century records of the Juchnewicz families of Girdziunai village in Lithuania. But genealogy is more than the obsessive collection of baptisms, marriages, and deaths. The study of family history is also the study of history. Musings traverses the sometimes grim, sometimes odd, events that occurred at the fact-jammed intersection of family history and history—a Revolutionary War massacre, the Black Tom munitions explosion in 1916, the embarkation of troops from Hoboken in World War I, the Women’s Army Corps in World War II, the lives o...