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The Molecular Basis of Human Cancer
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Cancer Prevention and Screening
Winner of the Council Chair's Choice Award at the 2019 British Medical Association Awards. Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques
Molecular Pathology of Lung Cancer
As with other books in the Molecular Pathology Library Series, Molecular Pathology of Lung Cancer bridges the gap between the molecular specialist and the clinical practitioner, including the surgical pathologist who now has a key role in decisions regarding molecular targeted therapy for lung cancer. Molecular Pathology of Lung Cancer provides the latest information and current insights into the molecular basis for lung cancer, including precursor and preinvasive lesions, molecular diagnosis, molecular targeted therapy, molecular prognosis, molecular radiology and related fields for lung cancer generally and for the specific cell types. As many fundamental concepts about lung cancer have undergone revision in only the past few years, this book will likely be the first to comprehensively cover the new molecular pathology of lung cancer. It provides a foundation in this field for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, thoracic radiologists and their trainees, physician assistants, and nursing staff.
Lung Diseases and Cancer
The coexistence of lung disease and cancer in the same person is a frequent occurrence. Evidence suggests that this coexistence sometimes goes beyond chance; in fact, both disease types are associated and the presence of one can be a risk factor or a protective factor for the other. In this Monograph, the Guest Editors bring together renowned clinical and scientific experts to provide an exhaustive review of the bidirectional relationship between respiratory diseases and cancer (not just lung cancer). The chapters: explore the common causal pathways of cancer and lung disease; consider the diseases from an epidemiological, clinical and therapeutic point of view; and discuss the many ways in which they interact to influence patient management. The result is a book that will generate a better understanding of this relationship, giving rise to a greater awareness of the possible development of lung disease in people with cancer, and of the different types of cancer that are frequently seen in those with lung diseases.
Lung Cancer
Lung cancer is the most common cause of death from cancer worldwide – it is estimated to cause nearly one in five cancer deaths. Most lung cancer patients are diagnosed late and for many of them, there are currently no curative therapy options available, meaning long-term survival is still low. Nevertheless, enormous progress has been made in the field during the last decade. This Monograph provides a comprehensive overview of the current knowledge of and advances in lung cancer, covering areas such as: screening; tobacco control; COPD; diagnosis; therapy; and treatment of early stage lung cancer from both a surgeon’s and radiation oncologist’s perspective. Very recent achievements in innovative fields, such as targeted therapies and immunotherapies, are also discussed.
Molecular Pathology of Early Cancer
This book describes the principles and the application of the existing molecular methodology for the detection of early cancer. Discussion focuses on the molecular changes characterizing preneoplastic lesions; molecular targets for early detection; validation of molecular targets; and new diagnostic technology for early detection. The advantages of molecular detection over current methods are examined, as well as the importance of identifying and characterizing preneoplastic lesions. In addition to the uses of highly specific molecular probes to detect early cancer, this book demonstrates the many ways in which molecular markers serve oncology. While meeting pressing needs in the practice of medicine, molecular detection of early cancer scientifically necessitates a confrontation with the biology of cancer, such as the genetic determinants of progression, regression, dormancy, and invasion. This work not only discusses the diagnostic value of these molecular methods but views their practical benefits against a background of conventional morphology.
Indigenous and Tribal Peoples and Cancer
Although cancer survival has improved markedly in developed countries in recent decades, not all groups have benefited equally. In particular, Indigenous and Tribal peoples continue to have poorer cancer outcomes than their non-Indigenous counterparts. The available evidence suggests these disparities are linked to a complex combination of factors, including higher incidence of cancers associated with a high case fatality, later stage of diagnosis, reduced access to cancer treatment, and poorer overall health. Much research is underway to explore approaches to improving health system responses for Indigenous and Tribal peoples. A developing evidence base is supporting effective translation o...
Modern Thoracic Oncology (In 3 Volumes)
Modern Thoracic Oncology is the first comprehensive publication on thoracic oncology. Contributors who are world experts have authored concise, relevant and current topics in this field. Whether one desires information regarding lung cancer screening, esophageal cancer staging, mutational analysis, targeted therapies, stereotactic ablative radiation with real-time imaging, minimally-invasive and robotic surgery, combination immunotherapy, microwave/cryoablation, or methods of early cancer detection, this set of three volumes, encompass all of the latest information in the field of thoracic oncology. A rapidly advancing knowledgebase has led to dramatic improvements in individualized or 'pers...
