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Prion Proteins
Genetics of Prion Disease, by S. Lloyd, S. Mead and J. Collinge. Atypical Prion Diseases in Humans and Animals, by M. A. Tranulis, S. L. Benestad, T. Baron and H. Kretzschmar. Chronic Wasting Disease, by S. Gilch, N. Chitoor, Y. Taguchi, M. Stuart, J. E. Jewell and H. M. Schätzl. Transgenic Mouse Models and Prion Strains, by G. C. Telling. Neuroprotective and Neurotoxic Signaling by the Prion Protein, by U. K. Resenberger, K. F. Winklhofer and J. Tatzelt. Prion Seeded Conversion and Amplification Assays, by C. D. Orrú and B. Caughey. Prion Protein and Its Conformational Conversion: A Structural Perspective, by W. K. Surewicz and M. I. Apostol. Molecular Dynamics as an Approach to Study Prion Protein Misfolding and the Effect of Pathogenic Mutations, by M.W. van der Kamp and V. Daggett. Chemical Biology of Prion Protein: Tools to Bridge the In Vitro/Vivo Interface, by R. Seidel and M. Engelhard. The PrP-Like Proteins Shadoo and Doppel, by D. Westaway, N. Daude, S. Wohlgemuth and P. Harrison. Fungal Prions: Structure, Function and Propagation, by M. F. Tuite, R. Marchante and V. Kushnirov.
Streptococcal Infections
Streptococcal Infections: Clinical Aspects, Microbiology, and Molecular Pathogenesis offers an in-depth examination of the spectrum of hemolytic streptococcal infections and their complications. Additionally, the volume incorporates and discusses aspects of pneumococcal, entrococcal, and oral streptococcal disease. The recent resurgence of rheumatic fever, concomitant outbreaks of severe systemic group A streptococcal infections (often accompanied by toxic shock), an increasing incidence of multiple antibiotic resistance among streptococcal species, and an intensified effort to develop effective streptococcal vaccines have brought renewed attention to the continuing role of streptococci for ...
Numerical Methods for Flows
This book includes selected contributions on applied mathematics, numerical analysis, numerical simulation and scientific computing related to fluid mechanics problems, presented at the FEF-“Finite Element for Flows” conference, held in Rome in spring 2017. Written by leading international experts and covering state-of-the-art topics in numerical simulation for flows, it provides fascinating insights into and perspectives on current and future methodological and numerical developments in computational science. As such, the book is a valuable resource for researchers, as well as Masters and Ph.D students.
Making the Rugby World
This book explores the expansion of rugby from its imperial and amateur upper-class white male core into other contexts throughout the late nineteenth and twentieth centuries. The development of rugby in the racially divided communities of the setter empire and how this was viewed are explored initially. Then the editors turn to four case studies of rugby's expansion beyond the bounds of the British Empire (France, Italy, Japan and the USA). The role of women in rugby is examined and the subsequent development of women's rugby as one of the fastest growing sports for women in Europe, North America and Australasia in the 1980s and 1990s. The final section analyses the impact of commercialisation, professionalisation and media on rugby and the impact on the historic rugby culture linked to an ethos of amateurism.
Surgery in Multimodal Management of Solid Tumors
Surgery continues to be the most effective treatment of solid tumors in terms of recovery, while its combination with other treatments improves the survival curves especially in the advanced forms of the disease. The aim of my task first of all has been to provide readers with both the current and constantly evolving pathophysiologic knowledge required for building the foundation of a specific education enabling surgeons to meet the fundamental targets in surgical oncology. Secondly, this volume aims to present an update on the real possibilities offered by the cooperation between surgeon and pathologist and by chemotherapy, radiotherapy and gene therapy in the treatment of tumors in the lig...
Seafood and Freshwater Toxins
The last few years have brought about many changes in the field of marine and freshwater toxins, with advances in analytical technology and the realization that these toxins are a global issue. Offering a complete reference guide, Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Third Edition addresses all aspects of the social and scientific influence of phytotoxins, from legislation and monitoring to new drug development. Covering many new topics, the book examines three main aspects: monitoring of toxins; chemical, mechanistic, and toxicological diversity; and detection technologies. New to this edition: 35 new chapters and 5 updated chapters A focus on state-of-the...
Hedgehog Signaling
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on hedgehog signaling. Contributions from leading authorities Informs and updates on all the latest developments in the field
The Nazi Olympics
The 1936 Olympic Games played a key role in the development of both Hitler’s Third Reich and international sporting competition. The Nazi Olympics gathers essays by modern scholars from prominent participating countries and lays out the issues--sporting as well as political--surrounding the involvement of individual nations. The volume opens with an analysis of Germany’s preparations for the Games and the attempts by the Nazi regime to allay the international concerns about Hitler’s racist ideals and expansionist ambitions. Essays follow on the United States, Great Britain, and France--top-tier Olympian nations with misgivings about participation--as well as Germany's future Axis partners Italy and Japan. Other contributions examine the issues involved for Finland, Sweden, Norway, Denmark, and the Netherlands. Throughout, the authors reveal the high political stakes surrounding the Games and how the Nazi Olympics distilled critical geopolitical issues of the time into a spectacle of sport.
