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CephsInAction: Towards Future Challenges for Cephalopod Science
The last five years have been extremely challenging, but also very innovative for cephalopod science, and the outstanding tradition of biological contribution with cephalopod molluscs as key players in science and human activities and interests has continued. This Research Topic is one of several dedicated to cephalopod molluscs (e.g., Hanke and Osorio, 2018; Ponte et al., 2018) hosted by Frontiers over the last few years, not to mention other papers published separately. Highlighting of cephalopod science is important because it has much to offer not only the life science community, but also more broadly the public perception of science and its understanding and relationship with scientific...
Nematodes as Model Organisms
Nematodes are small multicellular organisms that have been used as biological models since the 1960s. For example, Caenorhabditis elegans is a free-living nematode worm, about 1mm in length, that lives in temperate soil environments. It is made up of about 1000 cells, and has a short life cycle of only two weeks. It was the first multicellular organism to have its whole genome sequenced. The book summarizes the importance of nematodes as model organisms in the fields of genetics, developmental biology, neurobiology, pharmacology, nutrition, ecology and parasitology. Of interest to a broad audience across a wide spectrum of disciplines, this book is useful for biologists working on comparative studies to investigate biological processes across organisms; medical scientists and pharmacologists for exploration of drugs and medicine (including the use of genome editing to eliminate diseases); ecologists considering nematodes as indicators for environment changes; and parasitologists for host-parasite interactions. Many other researchers can use this book as a benchmark for the broad implications of nematology research on other aspects of science.
Antiparasitic and Antibacterial Drug Discovery
Addressing parasitic diseases and those caused by bacteria, this much needed reference and handbook provides a unique insight into the approach adopted by commercial science towards infectious diseases, including the work of medicinal chemists. Many of the authors are scientists with hands-on experience of drug discovery units within the pharmaceutical industry. In addition, the text covers efforts towards drug development in infectious diseases from academic groups and non profit organizations.
Advances in Parasitology
Advances in Parasitology, Volume 123, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history. Informs and updates on all the latest developments in the field of parasitology Includes medical studies of parasites of major influence Features reviews of more traditional areas, such as zoology, taxonomy, and life history which help shape current thinking and applications
Parasitic Helminths
This third volume in the successful 'Drug Discovery in Infectious Diseases' series is the first to deal with drug discovery in helminthic infections in human and animals. The result is a broad overview of different drug target evaluation methods, including specific examples of successful drug development against helminthes, and with a whole section devoted to vaccine development. With its well-balanced mix of high-profile contributors from academia and industry, this handbook and reference will appeal to a wide audience, including parasitologists, pharmaceutical industry, epidemiologists, and veterinary scientists.
The Evolution of Neuropeptides – A Stroll Through the Animal Kingdom: Updates from the Ottawa 2019 ICCPB Symposium and Beyond
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Insects at the Center of Interactions with Other Organisms
(A) Figure from "Chami Kim-Jo, Jean-Luc Gatti and Marylène Poirié (2019). Drosophila Cellular Immunity Against Parasitoid Wasps: A Complex and Time-Dependent Process. Front. Physiol. 10:603. doi: 10.3389/fphys.2019.00603" (B) Figure from “Giuseppe Bari, Andrea Scala, Vita Garzone, Rosanna Salvia, Cem Yalcin, Pasqua Vernile, Antonella Maria Aresta, Osvaldo Facini, Rita Baraldi, Sabino A. Bufo, Heiko Vogel, Enrico de Lillo, Francesca Rapparini and Patrizia Falabella (2019). Chemical Ecology of Capnodis tenebrionis (L.) (Coleoptera: Buprestidae): Behavioral and Biochemical Strategies for Intraspecific and Host Interactions. Front. Physiol. 10:604. doi: 10.3389/fphys.2019.00604" (C) Figure f...
Cell Signalling in Prokaryotes and Lower Metazoa
Cell signalling lies at the heart of many biological processes and currently is the focus of intense research interest. In multicellular organisms, it is central to how different types of cell communicate with each other and how they detect and respond to extracellular signals. Intercellular communication is vital to single-celled organisms as well, allowing them to respond to environmental cues and signals. To date, much of the understanding of signalling mechanisms has come from research on specific cell types (eg mouse lymphocyte and cardiomyocyte) or on organisms in which communication systems such as nervous and endocrine systems are well established. This volume therefore aims to 'fill the gap' by concentrating on 'simple organisms' where the elements of those signalling systems first evolved. Many of the groups covered contain important pathogens or parasites, and the potential for manipulating signalling pathways for therapeutic intervention will be highlighted.
Neuropeptide GPCRs in neuroendocrinology
The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain.
The Biology of Nematodes
The Biology of Nematodes synthesizes literature on free-living, plant-parasitic, and animal-parasitic nematodes. Topics covered include systematics and phylogeny, neuromuscular physiology, locomotion, sense organs, behavior, aging, the nematode genome, survival strategies, immunology, structure and organization, gametes and fertilization, and feeding and metabolism. This volume, the most authoritative available, includes contributions from researchers working on groundbreaking molecular techniques leading to new approaches in the study of nematode worms. It provides an important resource for research scientists working in a number of agricultural, medical, and biological fields.
