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Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, ...
In Silico Chemistry and Biology: Current and Future Prospects provides a compact overview on recent advances in this highly dynamic branch of chemistry. Various methods of protein modelling and computer-assisted drug design are presented, including fragment- and ligand-based approaches. Many successful practical applications of these techniques are demonstrated. The authors also look to the future and describe the main challenges of the field.
It is thirty years since the technique of high-yield preparation of isolated hepatocytes, by collagenase perfusion of the liver, was published. The original method described by Berry and Friend has undergone many minor modifications by other workers, and the two-step procedure introduced by Seglen in 1976 has become the most frequent way to prepare hepatocyte suspensions. An important development introduced by Bissell in 1973 was the use of the cells as the first step in monolayer culture. The availability of the isolated hepatocyte preparation as cells in suspension or culture has undoubtedly facilitated research on the liver. This was emphasised in our book, published (with Dr. Greg Barrit...
Membrane processes today play a signifi cant role in the replacement therapy for acute and chronic organ failure diseases. Current extracorporeal blood purifi cation and oxygenation devices employ membranes acting as selective barriers for the removal of endogeneous and exogeneous toxins and for gas exchange, respectively. Additionally, membrane technology offers new interesting opportunities for the design of bioartificial livers, pancreas, kidneys, lungs etc. This book reviews the latest developments in membrane systems for bioartificial organs and regenerative medicine, investigates how membrane technology can improve the quality and efficiency of biomedical devices, and highlights the de...
In recent years there have been tremendous advances in the fields of chemistry, physics and biology which have a direct impact on advances in biomaterials science. Many areas of healthcare depend upon the development of novel biomaterials. This book contains contribution from scientists who have made numerous innovative and exciting advances in the field of biomedical materials. The latest advances in the field are covered including studies of cell interactions with biomaterials. The assessment of the potential applications for the development of new biomaterials, tissue engineering and future medical devices are discussed. It will also provide an opportunity to discuss the latest developments in the field and the vision for the future. The book clearly illustrates how basic and applied research are being combined to produce novel biomaterials.
Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as regenerative medicine, pharmaceuticals and tissue engineering. In addition...
Since the development of the first modules, hollow fibers have totally revolutionized the world of membranes—thanks to the new technological breakthroughs and innovative materials discovered. The importance of a book putting hollow fibers in the spotlight owes to this type of configuration being more and more appreciated, particularly in large-scale applications. Moreover, the advent of nanofibers has injected new vitality in biomedical research, air and water separation and filtration processes, and emerging areas of nanotechnology. This book singles out and highlights the unique properties that hollow fibers and nanofibers display in the fields where they already represent the dominant configuration and where their full exploitation is still hindered by economic and technological constraints.
This is an interdisciplinary book for biomimetic nanotechnology, that correlates the biology on the molecular scale with nanotechnology mimicking human senses and movement. The introduction provides the background in life science, chemistry, material science, and engineering needed to understand sensors and movement on the molecular level. The chapters discuss human movement, vision, smell and taste, hearing, and touch. Each chapter explains the sense or movement on the molecular level, then discusses nanotechnology that uses the human molecules or mimics the function of the human sense and movement on the nanoscale. This is an excellent book for senior undergraduates and graduate students in the life sciences, chemistry, material sciences, and engineering. It will also appeal to any reader with an interest in life sciences and nanotechnology.
Plasma decontamination is a rapidly expanding area of modern science and engineering. An increasing number of engineers are using plasma methods for decontamination of chemical and biological agents. Plasma decontamination is effectively applied today to clean and sterilize different surfaces, high volume air and water streams, industrial exhausts, and even living tissue of animals and humans. This book provides a fundamental introduction to virtually all aspects of modern plasma decontamination, as well as the most recent technological achievements in the area. The book is segmented into four specific sections of modern plasma decontamination: (1) plasma bio-decontamination, including disinfection and sterilization of surfaces, water and air streams; (2) plasma decontamination of chemical agents, including cleaning of air, water, and industrial exhaust gases from different pollutants and especially volatile organic compounds VOC; (3) plasma treatment of living tissue, including different subjects of plasma medicine from skin sterilization to tissue engineering; (4) major electric discharges applied for the plasma-assisted decontamination of chemical and biological agents.