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The implication of tumour microenvironment (TME) on cancer progression and therapeutic response has profoundly shifted the paradigms of molecular cancer research and drug discovery. The intricate networks of immune-inflammatory cells and signalling, cancer-associated fibroblasts, endothelial cells and adipose cells are extensively researched for diagnostics, therapeutics and predictive values. This includes siRNA and miRNA nanotherapeutics targeting these molecular components, owing to their powerful gene-silencing properties. Despite the concerted effort in the development of drug targeting TME, such as BLZ945 (a colony-stimulating factor-1 receptor inhibitor), there is a void in clinically satisfactory drug to target this intricate factor, thus far.
This book gathers the proceedings of the 11th International Conference on Frontier Computing, held in Seoul, on July 13–17, 2021, and provides comprehensive coverage of the latest advances and trends in information technology, science, and engineering. It addresses a number of broad themes, including communication networks, business intelligence and knowledge management, Web intelligence, and related fields that inspire the development of information technology. The respective contributions cover a wide range of topics: database and data mining, networking and communications, Web and Internet of things, embedded systems, soft computing, social network analysis, security and privacy, optical communication, and ubiquitous/pervasive computing. Many of the papers outline promising future research directions, and the book benefits students, researchers, and professionals alike. Further, it offers a useful reference guide for newcomers to the field.
According to the Chinese zodiac, 2018 was the year of the ‘earthly dog’. In the middle of the long, hot, and feverish dog days of the summer of 2018, some workers at Shenzhen Jasic Technology took their chances and attempted to form an independent union. While this action was met by the harshest repression, it also led to extraordinary demonstrations of solidarity from small groups of radical students from all over the country, which in turn were immediately and severely suppressed. China’s year of the dog was also imbued with the spirit of another canine, Cerberus—the three-headed hound of Hades—with the ravenous advance of the surveillance state and the increasing securitisation of Chinese society, starting from the northwestern region of Xinjiang. This Yearbook traces these latest developments in Chinese society through a collection of 50 original essays on labour, civil society, and human rights in China and beyond, penned by leading scholars and practitioners from around the world.
The 2022 International Conference on Information Economy, Data Modeling and Cloud Computing (ICIDC 2022) was successfully held in Qingdao, China from June 17 to 19, 2022. Under the impact of COVID-19, ICIDC 2022 was held adopting a combination of online and offline conference. During this conference, we were greatly honored to have Prof Datuk Dr Hj Kasim Hj Md Mansur from Universiti Malaysia Sabah, Malaysia to serve as our Conference Chairman. And there were 260 individuals attending the conference. The conference agenda was composed of keynote speeches, oral presentations, and online Q&A discussion. The proceedings of ICIDC 2022 cover various topics, including Big Data Finance, E-Commerce a...
Toxic metals are a class of chemical elements that, in certain concentrations, can cause damage to the health of humans and animals, in addition to impacting ecosystems. These metals are emitted to the environment mainly by anthropological sources, such as industries, extractive processes and burning of fossil fuels. This book presents the main sources of toxic metals emission, demonstrate the state of the art of waste disposal and valuation techniques, especially solids and wastewater treatment.
This book constitutes the proceedings of the 13th Pacific Rim Conference on Multimedia, held in Singapore during December 4-6, 2012. The 59 revised full papers presented were carefully reviewed and selected from 106 submissions for the main conference and are accompanied by 23 presentations of 4 special sessions. The papers are organized in topical sections on multimedia content analysis, image and video processing, video coding and multimedia information processing, image/video processing and analysis, video coding and multimedia system, advanced image and video coding, cross media learning with structural priors, as well as efficient multimedia analysis and utilization.
This Handbook illustrates the diverse and complex nature of industrial hubs and shows how industrial hubs promote industrialization, economic structural transformation, and economic catch-up.
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The concept of Big Data has become increasingly familiar in recent years, and it is already an indispensible tool in the management of everything from supply chains and transport to health and education. This book presents the proceedings of MMBD 2023, the 4th International Conference on Modern Management based on Big Data, held in Seoul, South Korea, from 1-4 August 2023. The 50 papers included here were selected from total of around 160 submissions after a rigorous review process. Papers delivered at the conference were divided into 3 main categories: Big Data, Modern Management, and a special session devoted to Big Data-driven manufacturing and service-industry supply-chain (SC) managemen...