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International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Metastasis of Breast Cancer
Written by experts in the subject area, the book covers a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis and diagnosis. This timely book also covers the current treatment options.
New Frontiers in Cytology
Diagnostic cytology has recently enjoyed increased attention and significance in modern research. Essential information on latest developments in methods and applications in cytology is provided by this book. Chapters review methodological advances, such as in cancer detection, and explore potential relationships to molecular biology. Also discussed are: viral infection, fundamentals of quantitative methods, and the revolutionary role of immunocytochemistry in diagnostic cell typing. The new insights offered by transmission and scanning electron microscopy into cellular structure and function are discussed, and the connections between cytology and histology are highlighted. Epidemiology in connection with cytology is incorporated in special reports. The current developments described here will become routine methods of the cytology of tomorrow.
Attempts to Understand Metastasis Formation I
In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The pu-rpose of these three volumes is to review the recent progress in molecular metas tasis research and to attempt to further understand the biol ogy of this multifocal process. With respect to present day molecular biology, the pioneers of metastasis research established the basic concepts of metasta sis formati...
Minimal Neoplasia
Minimal neoplasia may be defined as a small cancer that has progressed beyond its site of primary origin into the surrounding tissue, but that has not yet reached the stage of deeper invasion or metastasization. The basic principles of this minimal cancer are presented in chapters on molecular, biological and experimental aspects, and, in particular, on the clinical manifestations in various organs: preleukemia, incipient lymphoma, and minimal carcinomas of the uterine cervix, breast, thyroid, larynx, lung, prostate, stomach and colon. A separate chapter is devoted to cryptic gliomas. The latest morphological methods including cytology, early clinical diagnostics and, in particular, radiodiagnostics, are considered. The reader can expect up-to-date information about prompt diagnosis of the very early manifestations of cancer, together with inferences on therapy, which, especially in tumors of the uterine cervix, breast and thyroid, differs considerably from the treatment of advanced neoplasia.
Carbohydrate Chemistry
A review of coverage relevant to the chemistry of monosaccharides and oligosaccharides in a given year.
Introduction to Tumor Biology
This book offers clinical oncologists an introduction to some selected topics of tumor biology where important progress has been made during the last decade. The concept is rather unique because it combines advances in clinical pathology, genetics, molecular oncology and immunology.The first two chapters deal with the genetic and molecular basis of malignant transformation on cellular level: DNA damage, mutations and repair mechanisms, oncogenes and tumor suppressor genes. The growth of a tumor cell population depends not only on cell division, but also on deregulation of apoptosis (chapter 3). Most clinical tumors are charcterised by heterogeneity caused by different degrees of differentiat...
Antitumor Drug Radiation Interactions
This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions on the relative merits of experimental data derived from animal versus human tumors. This book also presents a section on the potential for new model systems or alternative test procedures for evaluating therapeutic benefits and cytotoxicities. Results of randomized clinical studies are reviewed with emphasis on recent studies involving protocols specifically designed to test the benefits from optimal integration of chemotherapy with radiotherapy. This book is intended for laboratory researchers in the field and clinicians interested in using the combined modality approach. It is also a useful resource for radiologists, oncologists, and all those interested in cancer research.
