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Hoops
From its early days as a sport to build “muscular Christianity” among young men flooding nineteenth-century cities to its position today as a global symbol of American culture, basketball has been a force in American society. It grew through high school gymnasiums, college pep rallies, and the fits and starts of professionalization. It was a playground game, an urban game, tied to all of the caricatures that were associated with urban culture. It struggled with integration and representations of race. Today, basketball’s influence seeps into film, music, dance, and fashion. Hoops tells the story of the reciprocal relationship between the sport and the society that received it. While ma...
Army Directory
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Reports
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Drug Transporters in Drug Disposition, Effects and Toxicity
This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Transporters are known determinants of drug disposition and efficacy/toxicity. In general, they are divided into solute carrier (SLC) and ATP binding cassette (ABC) families, and are located along cell membranes, where they mediate drug uptake into cells and export out of cells. Drug transporters are essential in maintaining cell homeostasis, and their gene mutations may cause or contribute to severe human genetic disorders, such as cystic fibrosis, neurological disease, retinal degeneration, anemia, a...
