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The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of graduate students, medical students, interns and fellows.
This volume is the third in the series Recent Advances in Orthopedics, bringing orthopaedic surgeons, musculoskeletal research scientists and trainees fully up to date with the latest advances in the field. Divided into seven sections, each chapter discusses new techniques and technologies for the management of disorders in the different musculoskeletal subspecialties, explaining the basic science and its clinical applications. Topics include biofilm-related infections, skeletal adaptation to load, biomarkers for musculoskeletal disease, degenerative disk disease, hip disease, fibrosis and post-traumatic joint stiffness, and microenvironmental cues in tendon injury and repair. Each chapter highlights the latest developments in the relevant musculoskeletal research. Edited by renowned, US-based experts, this resource is further enhanced by clinical photographs and figures. The previous volume (9789352702879) published in 2018.
Recent Advances in Spinal Surgery is a comprehensive, illustrated collection of the most recent developments in the field. An editorial team of US-based experts ensures authoritative content throughout. Divided into seventeen chapters, this book covers the full spectrum of spinal conditions and interventions. All information is thoroughly up-to-date, including reviews of novel neuroprotective and neuroregenerative strategies, and new tools for predicting surgical outcomes and collecting data. Recent Advances in Spinal Surgery also features discussion on surgical options for patients for whom non-operative interventions are unsuccessful, and covers total disc replacement for both the cervical and lumbar spines. 88 full colour illustrations enhance this important update in the field of spinal surgery. Key Points Reviews of the most recent developments in the field of spinal surgery New neuroprotective and neuroregenerative strategies for spinal cord injuries 88 full colour illustrations
Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world's most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz's The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today's newest developments in your practice. - Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. - Offers a newly revised, streamlined format that makes it easier than ever to find the in...
Consists of the transactions of the 22nd- annual meeting of the society.
Manufacturing Techniques for Materials: Engineering and Engineered provides a cohesive and comprehensive overview of the following: (i) prevailing and emerging trends, (ii) emerging developments and related technology, and (iii) potential for the commercialization of techniques specific to manufacturing of materials. The first half of the book provides the interested reader with detailed chapters specific to the manufacturing of emerging materials, such as additive manufacturing, with a valued emphasis on the science, technology, and potentially viable practices specific to the manufacturing technique used. This section also attempts to discuss in a lucid and easily understandable manner the...
Of the 121,000 people on donor lists in the U.S., over 100,000 need kidney transplants and thousands die each year while waiting. Bioprinting aspires to build healthy kidney tissue from a patient's own cells and transplant this to boost failing kidneys without fear of rejection... As the 21st century dawned, a handful of inspired scientists tried to use 3D printing to create living human tissue. Their vision was to restore the health of people with intractable injuries, such as worn out cartilage, severed nerves, ailing kidneys, failing heartsthe gamut of human frailties. Their modest success energized others to join the quest. Now, after two decades of ingenious effort and hard work, they h...
Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those ...
Advances in manufacturing and industrial engineering in terms of advanced and latest technologies are required nowadays to attend the accelerated demands of high quality, productivity, and sustainability simultaneously. This book fulfils the requirement by offering unique comprehensive chapters on advances in manufacturing and industrial engineering technologies with an emphasis on Industry 4.0. This book sheds light on advances in the field of manufacturing and industrial engineering for enhancement in productivity, quality, and sustainability. It comprehensively covers the recent developments, latest trends, research, and innovations being carried out. 3D printing, green manufacturing, com...