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This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology. Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates. Also, additional mechanistic evidence is presented for better understanding...
Multidisciplinary research involving crystallography, kinetic studies, molecular docking, genetics and other techniques in biochemistry has yielded a wealth of knowledge about the reaction mechanisms in cellular processes. This knowledge has allowed researchers to understand, in a better way, the normal functioning of the cell process, which is used as a reference point for learning about and preventing or correcting pathologies that cause diseases. This enzymology reference is a thorough compendium about reaction mechanisms occurring between the major enzymes related to the biosynthetic pathways of 3 important types of biological compounds – 6-carbon carbohydrates, fatty acids and amino a...
This book contains the best known approaches for preparing the main types of glycosides in a short and comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates for detection of gene markers in plant biotechnology. Special attention is made on the structural characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug design course.
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This book entitled 'Advances in Pharmacognosy and Phytochemistry of Diabetes’ uncovers the longstanding tradition of using medicinal plants to treat diabetes, showcasing their growing popularity due to effective results and fewer side effects compared to conventional therapies. As the global prevalence of diabetes continues to rise, the book addresses the increasing inclination towards natural remedies for managing this condition. The content covers the use of plants in diabetes treatment, the therapeutic potential of phytochemicals, and how these natural compounds target various human metabolic pathways. With a focus on simplicity, the book provides insights into the diverse classes of ph...
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
In a world of declining fossil energy, biotechnology explores multiple products and processes hidden in the rich genome of microbes, plants and animals. One of the reasons for the renewed spirit of biotechnology is supported by its capacity to swiftly incorporate the multidisciplinary advances in basic and applied sciences. This book presents a wide range of biotechnology research by the UPIBI community, teachers and students in the past 24 years. Novel methodologies, basic results and new processes are reported in several of the most dynamic fields in biotechnology such as health, energy, food and environment. This effort will certainly be an inspiration for students wishing to join research teams, for academic colleagues in search of new knowledge and for professionals exploring novel ideas or innovative solutions.
Analyzes informality in Latin America, exploring root causes and reasons for and implications of its growth. This book uses two distinct but complementary lenses. It concludes that reducing informality levels and overcoming the "culture of informality" will require actions to increase aggregate productivity in the economy.
Selected, peer reviewed papers from the 3rd International Congress of Energy and Environment Engineering and Management, Portalegre, Portugal, 25th to 27th November 2009
Technical problems require technical solutions that are innovative, simple, cheap, robust and easy to maintain. This book lists 100 winning inventions in the first International Inventors Award competition, organized in Stockholm.