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The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there ha...
The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical rese...
The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research
This series of four video tapes, which is based on the demonstrations pre-recorded by Robert H Anderson and Anton E Becker, two prominent European morphologists, shows the essence of the abnormal morphology within carefully selected autopsy specimens, comparing the findings with appropriately dissected normal hearts, and supplementing the anatomic material with diagrams and cartoons. Accompanying these tapes is an explanatory book prepared with extensive full colour illustrations based on the specimens and diagrams used in the videos and supplemented by appropriate material from the extensive files of the authors.The introductory chapter of the book discusses the background to sequential seg...
This volume of the Inter-American Yearbook on Human Rights covers the year 2005 and is organized along the same lines as its predecessors. Part One provides general information concerning the Inter-American Commission on Human Rights, and Part Two contains information concerning the Inter-American Court of Human Rights. The print edition is available as a set of two volumes (9789004186941).
An award-winning historian's examination of impossible events at the dawn of modernity and of their enduring significance Accounts of seemingly impossible phenomena abounded in the early modern era--tales of levitation, bilocation, and witchcraft--even as skepticism, atheism, and empirical science were starting to supplant religious belief in the paranormal. In this book, Carlos Eire explores how a culture increasingly devoted to scientific thinking grappled with events deemed impossible by its leading intellectuals. Eire observes how levitating saints and flying witches were as essential a component of early modern life as the religious turmoil of the age, and as much a part of history as N...
First multi-year cumulation covers six years: 1965-70.
Urban realism in the tradition of E.L. Doctorow, William Kennedy, Philip Roth and Jimmy Breslin, "When Jack Was With Us" immerses the reader in neighborhood life in New York City from the late 1950's through the late 1960's. Unlike many other novels by Baby Boomers, this novel makes no attempt to sugarcoat or nostaligize; it presents life as the author saw it while growing up, in all its beauty and all its brutality. There is no single protagonist; a number of characters whose lives intertwine each seek to make the best out of their lives amid the rich and often volatile ethnic tapestry of New York, against the backdrop of social change as the novel moves from the somnolent 1950's through the turbulent 1960's. Each character struggles and finds his/her damnation or redemption amid a city that personifies a nation in flux. It is a "coming of age" not only for the characters but for the greater American collective psyche.
Includes entries for maps and atlases.