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Parasite Genomics Protocols, Second Edition expands upon the previous edition with current, detailed methodologies that have been adapted to research parasites in the post genomic era. With new chapters on parasite studies, helminth pathogens, and protocols for undertaking other large-scale ‘omics’ methodologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Parasite Genomics Protocols, Second Edition offers a wide-ranging collection of diverse methods and protocols for further study into these unique organisms.
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
Many papers in this volume re?ect, to some degree, the active, rapid economic developmentincertaingeographicareasintheworldsuchasChina,Japan,South Korea,and EasternEurope, which demand cooperative work,particularly co- erative engineering, more than ever. New concepts and new ideas of cooperative design, visualization, and engineering have emerged to meet the higher demand resulting from the economic development in these areas. Another trend among the papers in this volume is to apply existing concepts and methods to new application areas. The emergence of new concepts can be considered as a signal of fruitful research with its maturity in the ?eld. This can be found in the papers of this ye...
In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study in genomics and bioinformatics. Most studies in molecular evolution rely heavily on statistical procedures based on stochastic process modelling and advanced computational methods including high-dimensional numerical optimization and Markov Chain Monte Carlo. This book provides an overview of the statistical theory and methods used in studies of molecular evolution. It includes an introductory sect...
It's a critical cliché that Cervantes' Don Quixote is the first modern novel, but this distinction raises two fundamental questions. First, how does one define a novel? And second, what is the relationship between this genre and understandings of modernity? In Forms of Modernity, Rachel Schmidt examines how seminal theorists and philosophers have wrestled with the status of Cervantes' masterpiece as an 'exemplary novel', in turn contributing to the emergence of key concepts within genre theory. Schmidt's discussion covers the views of well-known thinkers such as Friedrich Schlegel, José Ortega y Gasset, and Mikhail Bakhtin, but also the pivotal contributions of philosophers such as Hermann Cohen and Miguel de Unamuno. These theorists' examinations of Cervantes's fictional knight errant character point to an ever-shifting boundary between the real and the virtual. Drawing from both intellectual and literary history, Forms of Modernity richly explores the development of the categories and theories that we use today to analyze and understand novels.
Comprehensive and accessible coverage from the basics to advanced topics in modern quantum condensed matter physics.
This publication is a compilation of papers presented at the Semiconductor Device Reliabi lity Workshop sponsored by the NATO International Scientific Exchange Program. The Workshop was held in Crete, Greece from June 4 to June 9, 1989. The objective of the Workshop was to review and to further explore advances in the field of semiconductor reliability through invited paper presentations and discussions. The technical emphasis was on quality assurance and reliability of optoelectronic and high speed semiconductor devices. The primary support for the meeting was provided by the Scientific Affairs Division of NATO. We are indebted to NATO for their support and to Dr. Craig Sinclair, who admin isters this program. The chapters of this book follow the format and order of the sessions of the meeting. Thirty-six papers were presented and discussed during the five-day Workshop. In addi tion, two panel sessions were held, with audience participation, where the particularly controversial topics of bum-in and reliability modeling and prediction methods were dis cussed. A brief review of these sessions is presented in this book.
This book explores the work of Sir John Tenniel, the artist who illustrated the first editions of Lewis Carroll's best-known works. Although Tenniel and Carroll parted ways after publication of Through the Looking-Glass, the artist's designs fixed in the public's mind images of Carroll's characters that thrive down to the present day.
Each chapter presents a detailed background of the described method, its theoretical foundations, and its applicability to different biomedical material. Updated chapters describe either the most popular methods or those processes that have evolved the most since the past edition. Additionally, a large portion of the volume is devoted to clinical cytometry. Particular attention is paid to applications of cytometry in oncology, the most rapidly growing area. - Contains 56 extensive chapters authored by world authorities on cytometry - Covers a wide range of topics, including principles of cytometry and general methods, cell preparation, tandardization and quality assurance, cell proliferation...
The battle for the United Planets hits a fever pitch as the galactic conqueror Mongul beats some of the rulers of the galaxy to death and then heads for Earth! The only thing standing in his way? Superman! Meanwhile, back on Earth, the truth that Clark Kent is Superman continues to spiral out all over the world, and now the Daily Planet’s competition is gunning for his wife, Lois Lane!