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Standards of Mouse Model Phenotyping
This is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.
Current Topics in Developmental Biology
This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The Series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
Literature-based Discovery
This is the first coherent book on literature-based discovery (LBD). LBD is an inherently multi-disciplinary enterprise. The aim of this volume is to plant a flag in the ground and inspire new researchers to the LBD challenge.
The Mouse in Biomedical Research
History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.
Cumulative Subject Index
This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The Series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
Metal Nanocomposites in Nanotherapeutics for Oxidative Stress-Induced Metabolic Disorders
This book highlights the role and mechanism of different metal nanocomposites toward oxidative stress-induced metabolic disorders including metabolic pathways affected by oxidative stress and related pathophysiology. The book includes an illustrative discussion about the methods of synthesis, characterization, and biomedical applications of metal nanocomposites. It focuses on the therapeutic approaches for metabolic disorders due to oxidative stress by nano delivery systems. Moreover, the book includes chapters on nanotherapeutic approaches toward different diseases, including diabetes mellitus, obesity, cardiovascular disorders, cancers, and neurodegenerative diseases such as Alzheimer's di...
The Nature of Life and Its Potential to Survive
This book looks at the persistence of life and how difficult it would be to annihilate life, especially a species as successful as humanity. The idea that life in general is fragile is challenged by the hardiness of microbes, which shows that astrobiology on exoplanets and other satellites must be robust and plentiful. Microbes have adapted to virtually every niche on the planet, from the deep, hot biosphere, to the frigid heights of the upper troposphere. Life, it seems, is almost indestructible. The chapters in this work examine the various scenarios that might lead to the extermination of life, and why they will almost always fail. Life's highly adaptive nature ensures that it will cling on no matter how difficult the circumstances. Scientists are increasingly probing and questioning life's true limits in, on and above the Earth, and how these limits could be pushed elsewhere in the universe. This investigation puts life in its true astronomical context, with the reader taken on a journey to illustrate life's potential and perseverance.
Perspectives on Auditory Research
Perspectives on Auditory Research celebrates the last two decades of the Springer Handbook in Auditory Research. Contributions from the leading experts in the field examine the progress made in auditory research over the past twenty years, as well as the major questions for the future.
