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Mycotoxin Protocols
Mycotoxins produced by molds are common contaminants of many important crops, including wheat, corn, rice, and peanuts. Some mycotoxins are found in fruits and vegetables. These contaminants have a broad range of toxic effects, including carcinogenicity, neurotoxicity, and reproductive and developmental toxicity. The occurrence of mycotoxins in foods is an unavoidable worldwide problem. About 80 countries have imposed regulatory limits to minimize human and animal exposure to mycotoxins. Regulatory limits, including international standards, have tremendous economic impact and must be developed using science-based risk assessments. The purpose of Mycotoxin Protocols is to provide the scientif...
Affinity Chromatography
Affinity chromatography, with its exquisite specificity, is based upon molecular recognition. It is a powerful tool for the purification of biomolecules. In recent years, numerous new applications and modified techniques have been derived from gro- specific interactions and biological recognition principles. An up-to-date review of the past, current, and future applications of affinity chromatography has been presented in the introductory chapter by Meir Wilchek and Irwin Chaiken. Though many of these new applications and techniques are well documented in the literature, it is often difficult to find methods that are written with the intent of helping new practitioners of affinity chromatogr...
Biodeterioration Research
Once again the present volume contains the majority of the papers presented at the Third Pan-American Biodeterioration Society Meeting held at The George Washington University, Washington, D.C., USA, on August 3, 4, 5, and 6, 1989. The sponsors for this symposium included The George Washington University, The Smithsonian Institution, The Virginia Department of Health, The University of Connecticut, The National Institute for Occupational Safety and Health, Clark Atlanta University, Ball State University, the U.S. Naval Research Laboratory, the Agriculture Research Service/U. S. Department of Agriculture, the University of Georgia, the Metropolitan Museum of Art, Morehouse College, the Univer...
Mycotoxins in Agriculture and Food Safety
Describes a range of mycotoxins occurring as contaminants in agricultural crops and animal products, and details the implementation of food safety regulations via governmental and international agencies. The book charts the progress made in mycotoxicology since the early 1990s. It also profiles recent advances in mycotoxin analysis methods.
Pediatric Gender Assignment
This book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled "Pediatric Gender Assignment - A Critical Reappraisal". Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phen...
Selected Technical Publications
Each no. represents the results of the FDA research programs for half of the fiscal year.
Adipose Tissue Protocols
Adipose tissue is recognized to be exquisitely sensitive to hormone action, and is also now recognized as a secretory and endocrine organ required for reproduction and good health. Adipocytes are “smart” cells able within the tissue to communicate with surrounding cells, but also with various organs, particularly via leptin acting on the central nervous system. Brown adipose tissue (BAT) and white adipose tissue (WAT) are known to be distinct tissues, whereas the heterogeneity of WAT depots is well est- lished. Unfortunately, excess WAT leads to obesity, which is the most common health problem in industrialized countries. Therefore, from both a scientific and a technical point of view, t...
Methods of Analysis of Food Components and Additives
With diet, health, and food safety news making headlines on a regular basis, the ability to separate, identify, and analyze the nutrients, additives, and toxicological compounds found in food and food components is more important than ever. This requires proper training in the application of best methods, as well as efforts to improve existing meth
Biodeterioration Research 2
The present volume contains the majority of the papers presented at the Second Pan-American Biodeterioration Society Meeting held at The George Washington University, Washington, D.C., USA, on July 28, 29, 30, and 31, 1988. The sponsors for this symposium included The George Washington University, The Smithsonian Institution, The Virginia Department of Health, The University of Connecticut, The National Institute for Occupational Safety and Health, Atlanta University, Ball State University, the U.S. Naval Research Laboratory, the Agriculture Research Service/U.S. Department of Agriculture, and the University of Georgia. The program was organized by members of the Program and Planning Committ...
