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Recent developments in basic and applied science have led to better understanding of disease mechanisms and more efficient therapies for multiple sclerosis. The most effective way of managing these patients is through a carefully planned neurorehabilitation programme. The main aims are to reduce disability and handicap and improve functions through effective training, stimulating activity and social participation. As the first text on recovery of function and neurorehabilitation in MS, this book focuses on mechanisms of recovery, application of neuroplasticity to therapeutic interventions, and determination of the efficiency of these interventions. Basic principles of neurorehabilitation in MS are described, as well as techniques for treating specific syndromes which may occur in MS. Written and edited by leading clinicians and researchers, the book achieves an excellent balance between basic science, pathophysiology, and clinical rehabilitation. An essential resource for clinicians and therapists treating patients with multiple sclerosis, neurophysiologists, and health care advisors.
The thalamus is often described as a relay. Typified by sensory pathways, this concept leads to thalamic nuclei being viewed as areas that passively streams information from a single source to the cortex, without affecting the nature of that information. However, diverse intrathalamic connections, the varying synaptic and membrane properties of thalamic neurons and the large number of inputs from non-sensory sources make the idea that the thalamus is just a passive relay unlikely. Furthermore, a large number of thalamic nuclei are not primarily driven by sensory signals nor do they exclusively target the cortex, meaning the thalamus must do more than simply pass sensory signals to the cortex. Finally, there is a wealth of research demonstrating that the thalamus does indeed function in ways that are not captured by the concept of a simple relay. So why, given all of this, is the primary paradigm for describing the thalamus, a relay? This Research Topic covers original research, reviews and hypotheses on thalamic function that explore the concept that the thalamus performs computational tasks other than simply passively relaying information.
Antioxidants, Volume 121 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Vitamins and Hormones series - Updated release includes the latest information on Antioxidants
The book discusses nano-phytoremediation: the use of nanotechnology in combination with phytoremediation to restore polluted environs. The potentiality of plants in association with nanomaterials to effectively remediate polluted areas is elaborated meritoriously in this book. New strategies are necessary because anthropogenic actions represent a serious threat to life on Earth. This book has given enough space for a discussion of innovative and efficient technologies to restore damaged environs primarily focused on nano-phytoremediation. The first part of the book is dedicated to exploring organic and inorganic pollution and the threats they pose to living forms. The second part explores th...
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The book deals with the role of both oxygen- and nitrogen-centred free radicals in inflammatory diseases such as rheumatoid arthritis. The well-known involvement of the superoxide anion radical in the bactericidal action of inflammatory cells suggests that radicals and the inflammatory response are inextricably linked. The widespread involvement of radicals in human disease seems inevitable, because inflammation is such a conspicuous component of human disease. For the first time, the present text integrates contributions from leading research groups who have been investigating the role of radicals within the context of all stages of inflammtion, such as the recruitment of inflammatory cells...
Interest in the science of exercise dates back to the time of ancient Greece. Today exercise is viewed not only as a leisurely activity but also as an effective preventive and therapeutic tool in medicine. Further biomedical studies in exercise physiology and biochemistry reports that strenuous physical exercise might cause oxidative lipid damage in various tissues. The generation of reactive oxygen species is elevated to a level that overwhelms the tissue antioxidant defense systems resulting in oxidative stress.The Handbook of Oxidants and Antioxidants in Exercise examines the different aspects of exercise-induced oxidative stress, its management, and how reactive oxygen may affect the functional capacity of various vital organs and tissues. It includes key related issues such as analytical methods, environmental factors, nutrition, aging, organ function and several pathophysiological processes.This timely publication will be of relevance to those in biomedical science and was designed to be readily understood by the general scientific audience.
Computational Modeling of Infectious Disease: With Applications in Python provides an illustrated compendium of tools and tactics for analyzing infectious diseases using cutting-edge computational methods. From simple S(E)IR models, and through time series analysis and geospatial models, this book is both a guided tour through the computational analysis of infectious diseases and a quick-reference manual. Chapters are accompanied by extensive practical examples in Python, illustrating applications from start to finish. This book is designed for researchers and practicing infectious disease forecasters, modelers, data scientists, and those who wish to learn more about analysis of infectious disease processes in the real world. Connects computational infectious disease analysis to state-of-the-art data science Conveys ideas on epidemiology and infectious disease modeling in a clear, accessible way Provides code examples to elucidate best practices