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Advances in Clinical Chemistry
Volume 48 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting-edge microarray technology. * Leading experts from academia and clinical laboratory science * Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies
Mixed-Mode Modelling: Mixing Methodologies For Organisational Intervention
The 1980s and 1990s have seen a growing interest in research and practice in the use of methodologies within problem contexts characterised by a primary focus on technology, human issues, or power. During the last five to ten years, this has given rise to challenges regarding the ability of a single methodology to address all such contexts, and the consequent development of approaches which aim to mix methodologies within a single problem situation. This has been particularly so where the situation has called for a mix of technological (the so-called 'hard') and human centred (so-called 'soft') methods. The approach developed has been termed mixed-mode modelling. The area of mixed-mode model...
Advances in the Study of Genetic Disorders
The studies on genetic disorders have been rapidly advancing in recent years as to be able to understand the reasons why genetic disorders are caused. The first Section of this volume provides readers with background and several methodologies for understanding genetic disorders. Genetic defects, diagnoses and treatments of the respective unifactorial and multifactorial genetic disorders are reviewed in the second and third Sections. Certainly, it is quite difficult or almost impossible to cure a genetic disorder fundamentally at the present time. However, our knowledge of genetic functions has rapidly accumulated since the double-stranded structure of DNA was discovered by Watson and Crick in 1956. Therefore, nowadays it is possible to understand the reasons why genetic disorders are caused. It is probable that the knowledge of genetic disorders described in this book will lead to the discovery of an epoch of new medical treatment and relieve human beings from the genetic disorders of the future.
Make More Noise!
"You have to make more noise than anybody else" - Emmeline Pankhurst, leader of the British Suffragette movement An incredible collection of brand new short stories, from ten of the UK's very best storytellers, celebrating inspirational girls and women, being published to commemorate the 100th anniversary of women's suffrage in the UK. £1 from the sale of every book will be donated to Camfed, an international charity which tackles poverty and inequality by supporting women's education in the developing world. Featuring short stories by Kiran Millwood Hargrave, author of the Waterstones Children's Book Prize-wining The Girl of Ink and Stars, M.G. Leonard, author of Beetle Boy, Patrice Lawrence, author of the Waterstones Children's Book Prize-winning Orangeboy, Katherine Woodfine, author of The Mystery of the Clockwork Sparrow, Sally Nicholls, author of Things a Bright Girl Can Do, Emma Carroll, author of Letters from the Lighthouse, and more!
Ways To Live Forever
From award-winning author Sally Nicholls, her debut novel about a boy's last months with leukemia.1. My name is Sam.2. I am eleven years old.3. I collect stories and fantastic facts.4. I have leukemia.5. By the time you read this, I will probably be dead.Living through the final stages of leukemia, Sam collects stories, questions, lists, and pictures that create a profoundly moving portrait of how a boy lives when he knows his time is almost up.
Advances in Mitochondrial Medicine
Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are act...
