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In an important new contribution to the literature of chaos, two distinguished researchers in the field of physiology probe central theoretical questions about physiological rhythms. Topics discussed include: How are rhythms generated? How do they start and stop? What are the effects of perturbation of the rhythms? How are oscillations organized in space? Leon Glass and Michael Mackey address an audience of biological scientists, physicians, physical scientists, and mathematicians, but the work assumes no knowledge of advanced mathematics. Variation of rhythms outside normal limits, or appearance of new rhythms where none existed previously, are associated with disease. One of the most interesting features of the book is that it makes a start at explaining "dynamical diseases" that are not the result of infection by pathogens but that stem from abnormalities in the timing of essential functions. From Clocks to Chaos provides a firm foundation for understanding dynamic processes in physiology.
The first edition of this book was originally published in 1985 under the ti tle "Probabilistic Properties of Deterministic Systems. " In the intervening years, interest in so-called "chaotic" systems has continued unabated but with a more thoughtful and sober eye toward applications, as befits a ma turing field. This interest in the serious usage of the concepts and techniques of nonlinear dynamics by applied scientists has probably been spurred more by the availability of inexpensive computers than by any other factor. Thus, computer experiments have been prominent, suggesting the wealth of phe nomena that may be resident in nonlinear systems. In particular, they allow one to observe the i...
Exploration of Second Law of Thermodynamics details fundamental dynamic properties behind construction of statistical mechanics. Topics include maximal entropy principles; invertible and noninvertible systems; ergodicity and unique equilibria; and asymptotic periodicity and entropy evolution. Geared toward physicists and applied mathematicians; suitable for advanced undergraduate and graduate courses. 1992 edition.
This book shows how densities arise in simple deterministic systems. There has been explosive growth in interest in physical, biological and economic systems that can be profitably studied using densities. Due to the inaccessibility of the mathematical literature there has been little diffusion of the applicable mathematics into the study of these 'chaotic' systems. This book will help to bridge that gap. The authors give a unified treatment of a variety of mathematical systems generating densities, ranging from one-dimensional discrete time transformations through continuous time systems described by integro-partial differential equations. They have drawn examples from many scientific fields to illustrate the utility of the techniques presented. The book assumes a knowledge of advanced calculus and differential equations, but basic concepts from measure theory, ergodic theory, the geometry of manifolds, partial differential equations, probability theory and Markov processes, and stochastic integrals and differential equations are introduced as needed.
Introduces concepts from nonlinear dynamics using an almost exclusively biological setting for motivation, and includes examples of how these concepts are used in experimental investigations of biological and physiological systems. One novel feature of the book is the inclusion of classroom-tested computer exercises. This book will appeal to students and researchers working in the natural and physical sciences wanting to learn about physiological systems from a mathematical perspective.
First multi-year cumulation covers six years: 1965-70.
Ideal as a classroom text or for individual study, this unique one-volume overview of classical wave theory covers wave phenomena of acoustics, optics, electromagnetic radiations, and more.
Originally published: New York: Wiley, 1980.
The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels. A Systems Biology Approach to Blood is divided into three main sections: basic compo...
This mathematical reference for theoretical physics employs common techniques and concepts to link classical and modern physics. It provides the necessary mathematics to solve most of the problems. Topics include the vibrating string, linear vector spaces, the potential equation, problems of diffusion and attenuation, probability and stochastic processes, and much more. 1972 edition.