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Color Atlas and Textbook of Human Anatomy
Emphasizing clinical anatomy, the text integrates current information from an array of medical disciplines into the discussions of the nervous system and sensory organs, including in-depth coverage of key topics, including molecular signaling, the interplay between ion channels and transmitters, imaging techniques such as PET, CT, and NMR, and much more.
Genetic Control of Neuronal Migrations in Human Cortical Development
The early steps in corticogenesis are decisive for the correct unfolding of neurogenesis, neuronal migration and differentiation under tight genetic control. In this monograph, the author outlines the main events in human preplate formation according to their timetable of appearance and the expression of developmentally relevant gene products. Also examined are the gradual transformation of the preplate into the cortical plate, and the establishment of the transient compartments of the foetal cortical wall.
Valency over Time
Valency patterns and valency orientation have been frequent topics of research under different perspectives, often poorly connected. Diachronic studies on these topics is even less systematic than synchronic ones. The papers in this book bring together two strands of research on valency, i.e. the description of valency patterns as worked out in the Leipzig Valency Classes Project (ValPaL), and the assessment of a language's basic valency and its possible orientation. Notably, the ValPaL does not provide diachronic information concerning the valency patterns investigated: one of the aims of the book is to supplement the available data with data from historical stages of languages, in order to make it profitably exploitable for diachronic research. In addition, new research on the diachrony of basic valency and valency alternations can deepen our understanding of mechanisms of language change and of the propensity of languages or language families to exploit different constructional patterns related to transitivity.
Jasper's Basic Mechanisms of the Epilepsies
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
The Hippocampus Book
The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Studies in Gothic
This volume investigates a wide range of topics in the study of Gothic, the oldest Germanic language to be attested in any substantial texts, some three centuries before the earliest Old English. It covers issues in sociolinguistics, historical linguistics, phonology, derivational morphology, verbal syntax, and discourse structure. Individual chapters examine Gothic-Latin bilingualism in sixth-century Italy, some hitherto undiscovered aspects of the production of the first edition of the Codex Argenteus associated with England, and the translations of Greek nominal compounds in the Gospels. Phonological and morphological topics covered include vowel lowering (?breaking?), the distinction bet...
Brain Leitmotifs
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The Sound of Indo-European
This contribution in this volume discuss a large variety of issues from the realm of Indo-European phonology in its broadest definition, stretching from minute phonetic to more abstract levels of phonemics and morphophonemics and centering upon all varieties of Indo-European, including the protolanguage and its recent pre-stages and, in effect, all of its post-stages till this day.
Brain Repair
Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies. Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics. Thus, this book is unique in bridging the gap between basic and clinical research. It will be a valuable tool for all students, researchers and clinicians interested in understanding the brain's capacity to cope with lesions and interested in learning about emerging new therapy concepts.
